(S)-5-Hydroxymethyl-2(5H)-furanone

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Names

[ Name ]:
(S)-5-Hydroxymethyl-2(5H)-furanone

[Synonym ]:
(S)-5-Hydroxymethyl-2(5H)-furanone
(5S)-5-(Hydroxymethyl)-2(5H)-furanone
(5S)-5-(Hydroxymethyl)furan-2(5H)-one
(2S)-2-(hydroxymethyl)-2H-furan-5-one
MFCD05663651
2(5H)-Furanone, 5-(hydroxymethyl)-, (5S)-
(S)-5-Hydroxymethyl-2[5H]-furanone

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
334.8±17.0 °C at 760 mmHg

[ Melting Point ]:
41-43ºC(lit.)

[ Molecular Formula ]:
C₅H₆O₃

[ Molecular Weight ]:
114.099

[ Flash Point ]:
166.8±13.7 °C

[ Exact Mass ]:
114.031693

[ PSA ]:
46.53000

[ LogP ]:
-1.81

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.502

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

methyl (S)-4,5-dihydroxy-4,5-O-isopropylidene-2-pentenoate
(5S)-(5-tert-Butyldimethylsiloxymethyl)furan-2(5H)-one
2-Bromo-2-deoxy-D-arabinono-γ-lactone
(z)-ethyl-4,5-o-isopropylidene-(s)-4,5-dihydroxy-2-pentenoate
METHYL (S)-(+)-3-(2,2-DIMETHYL-1,3-DIOXOLAN-4-YL)-CIS-2-PROPENOATE
(5S)-5-(trityloxymethyl)-5H-furan-2-one
2,3-O-(ethoxymethylene)-D-ribonic acid γ-lactone
(R,E)-ETHYL 3-(2,2-DIMETHYL-1,3-DIOXOLAN-4-YL)ACRYLATE
[(2S)-5-oxo-2H-furan-2-yl]methyl acetate
methyl (Z)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)-2-propenoate

DownStream

(5S)-5-(Hydroxymethyl)dihydro-2(3H)-furanone
(r)-gamma-valerolactone
Zidovudine
Muscarine iodide
S(+)-DIHYDRO-5-TRITYLOXYMETHYL-2(3H)-FURANONE
2',3'-dideoxy-2',3'-methanocytidine
Protoanemonin
[(3R,3aS,6aR)-Hydroxyhexahydrofuro[2,3-b]furanyl Succinimidyl Carbonate
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol
(5S)-5-(trityloxymethyl)-5H-furan-2-one

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Bohrisch, J. et al.

Tetrahedron Lett. 34 , 2749, (1993)

(S)-(-)-2-Fluoro-4-(hydroxymethyl)-2-buten-4-olide
2(5H)-Furanone, 5-(hydroxymethyl)-3-methoxy-, (S)- (9CI)
(R)-(+)-5-(Hydroxymethyl)-2(5H)-furanone
3-(3-Chlorophenyl)-5-(hydroxymethyl)-2(5H)-furanone
(-)-(S)-5-pivaloyloxymethyl-2(5H)-furanone
(S)-5-(hydroxymethyl)-4-(methoxymethoxy)-3,5-dimethylfuran-2(5H)-one