Cycloastragenol

Suppliers

Names

[ Name ]:
Cycloastragenol

[Synonym ]:
9,19-Cyclolanostane-3,6,16,25-tetrol, 20,24-epoxy-, (3β,6α,9β,16β,20R,24S)-
Astramembrangenin
(3β,6α,9β,16β,20R,24R)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol
9,19-Cyclolanostane-3,6,16,25-tetrol, 20,24-epoxy-, (3β,6α,9β,16β,20R,24R)-
Cycloastragenol
(3β,6α,9β,16β,20R,24S)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol
Cyclosieversigenin
Cyclogalegigenin

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
617.2±55.0 °C at 760 mmHg

[ Melting Point ]:
241.0 to 245.0 °C

[ Molecular Formula ]:
C₃₀H₅₀O₅

[ Molecular Weight ]:
490.715

[ Flash Point ]:
327.1±31.5 °C

[ Exact Mass ]:
490.365814

[ PSA ]:
90.15000

[ LogP ]:
3.82

[ Vapour Pressure ]:
0.0±4.0 mmHg at 25°C

[ Index of Refraction ]:
1.582

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
GX8265000

[ HS Code ]:
2942000000

Customs

[ HS Code ]: 2942000000

Articles

Cycloastragenol is a potent telomerase activator in neuronal cells: implications for depression management.

Neurosignals 22(1) , 52-63, (2014)

Cycloastragenol (CAG) is an aglycone of astragaloside IV. It was first identified when screening Astragalus membranaceus extracts for active ingredients with antiaging properties. The present study de...

A novel telomerase activator suppresses lung damage in a murine model of idiopathic pulmonary fibrosis.

PLoS ONE 8(3) , e58423, (2013)

The emergence of diseases associated with telomere dysfunction, including AIDS, aplastic anemia and pulmonary fibrosis, has bolstered interest in telomerase activators. We report identification of a n...

Telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytes.

J. Immunol. 181(10) , 7400-6, (2008)

Telomerase reverse transcribes telomere DNA onto the ends of linear chromosomes and retards cellular aging. In contrast to most normal somatic cells, which show little or no telomerase activity, immun...