2-anilino-N-ethyl-6-methylpyridine-3-carboxamide

Names

[ CAS No. ]:
78593-73-4

[ Name ]:
2-anilino-N-ethyl-6-methylpyridine-3-carboxamide

[Synonym ]:
2-Anilino-N-ethyl-6-methylnicotinamide
Nicotinamide,2-anilino-N-ethyl-6-methyl

Chemical & Physical Properties

[ Density]:
1.15g/cm3

[ Boiling Point ]:
419ºC at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₇N₃O

[ Molecular Weight ]:
255.31500

[ Flash Point ]:
207.2ºC

[ Exact Mass ]:
255.13700

[ PSA ]:
57.51000

[ LogP ]:
3.53110

[ Index of Refraction ]:
1.608

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QS4000950

CHEMICAL NAME :: Nicotinamide, 2-anilino-N-ethyl-6-methyl-

CAS REGISTRY NUMBER :: 78593-73-4

LAST UPDATED :: 199803

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H17-N3-O

MOLECULAR WEIGHT :: 255.35

WISWESSER LINE NOTATION :: T6NJ BMR& CVM2 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 390 mg/kg

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic)

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,249,1981

Synthetic Route

Click to get detail synthetic route

Related Compounds

2-anilino-N-butyl-6-methylpyridine-3-carboxamide
5-amino-2-ethyl-6-methylpyridine-3,4-dicarbonitrile
N-ethyl-2-(4-methoxyanilino)-6-methylpyridine-3-carboxamide
2-anilino-5-hydroxy-6-methylpyridine-3-carboxylic acid
2-N-ethyl-6-hydrazinyl-1,3,5-triazine-2,4-diamine
2-N-ethyl-6-methylsulfanyl-1,3,5-triazine-2,4-diamine