Amorolfine hydrochloride

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Names

[ CAS No. ]:
78613-38-4

[ Name ]:
Amorolfine hydrochloride

[Synonym ]:
(2R,6S)-2,6-Dimethyl-4-{2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl}morpholine hydrochloride (1:1)
Loceryl
Locetar
Amorolfine Hydrochloride
(2R,6S)-2,6-Dimethyl-4-{2-methyl-3-[4-(2-methyl-2-butanyl)phenyl]propyl}morpholine hydrochloride (1:1)
MFCD00903738
Curanail
Amorolfine HCl
Odenil
Morpholine, 4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-, (2R,6S)-, hydrochloride (1:1)

Chemical & Physical Properties

[ Density]:
1.234

[ Boiling Point ]:
78-82°C (9 Torr)

[ Molecular Formula ]:
C21H36ClNO

[ Molecular Weight ]:
353.970

[ Exact Mass ]:
353.248535

[ PSA ]:
12.47000

[ LogP ]:
5.40190

[ Storage condition ]:
room temp

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H411

[ Precautionary Statements ]:
P301 + P312 + P330

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
26-36

[ RIDADR ]:
UN 3077 9 / PGIII

[ HS Code ]:
29411010

Customs

[ HS Code ]: 29411010

Articles

The low keratin affinity of efinaconazole contributes to its nail penetration and fungicidal activity in topical onychomycosis treatment.

Antimicrob. Agents Chemother. 58(7) , 3837-42, (2014)

Onychomycosis is a common fungal nail disease that is difficult to treat topically due to the deep location of the infection under the densely keratinized nail plate. Keratin affinity of topical drugs...

Characterization of Antifungal Activity and Nail Penetration of ME1111, a New Antifungal Agent for Topical Treatment of Onychomycosis.

Antimicrob. Agents Chemother. 60 , 1035-9, (2016)

Fungal nail infection (onychomycosis) is a prevalent disease in many areas of the world, with a high incidence approaching 23%. Available antifungals to treat the disease suffer from a number of disad...

Mechanism of Action of ME1111, a Novel Antifungal Agent for Topical Treatment of Onychomycosis.

Antimicrob. Agents Chemother. 60 , 873-80, (2016)

Despite the existing treatment options for onychomycosis, there remains a strong demand for potent topical medications. ME1111 is a novel antifungal agent that is active against dermatophytes, has an ...


More Articles

Related Compounds

  • Amorolfine hydrochloride
  • amorolfine
  • amorolfine
  • carnitine hydrochloride
  • Triprolidine hydrochloride
  • dodecylamine hydrochloride
  • rac-5-{2-[(1R,2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexyl]acetamido}pentanoic acid
  • (2S)-3-(dimethylamino)-2-{[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolan-3-yl]formamido}propanoic acid
  • (2S)-3-(dimethylamino)-2-[6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanamido]propanoic acid
  • 4-[(2S)-3-(dimethylamino)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-(propan-2-yl)propanamido]butanoic acid
  • 3-[(2S)-3-(dimethylamino)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-methylpropanamido]-2-methylpropanoic acid
  • 2-[(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanamido]spiro[3.3]heptane-2-carboxylic acid
  • rac-3-{2-[(1R,3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}oxolane-2-carboxylic acid
  • 2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanamido]oxy}propanoic acid
  • 2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpentanamido]oxy}propanoic acid
  • 2-{[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpentanamido]oxy}propanoic acid
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