8-OH-DPAT

Suppliers

Names

[ Name ]:
8-OH-DPAT

[Synonym ]:
2-dipropylamino-8-hydroxy-1,2,3,4-tetrahydronaphthalene
(+/-)-2-dipropylamino-7-hydroxy-1,2,3,4-tetrahydronaphthalene
(+/-)-2-dirpopylamino-7-hydroxy-1,2,3,4-tetrahydronaphthalene
8-OH-2-(di-n-propylamino)-1,2,3,4-tetrahydronaphthalene
3-(Dipropylamino)Tetralin-5-Ol
8-OH-DPAT

Chemical & Physical Properties

[ Boiling Point ]:
372.5ºC at 760 mmHg

[ Molecular Formula ]:
C₁₆H₂₅NO

[ Molecular Weight ]:
247.37600

[ Flash Point ]:
168.2ºC

[ Exact Mass ]:
247.19400

[ PSA ]:
23.47000

[ LogP ]:
3.37150

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

Articles

Serotonin 5-HT1A receptor in infancy-onset aggression: comparison with genetically defined aggression in adult rats.

Behav. Brain Res. 243 , 97-101, (2013)

Antisocial aggressive behavior in adolescents represents growing clinical and social problem. Previously the implication of 5-HT1A receptor in the regulation of fear-induced aggression was shown. Here...

Unilateral lesion of the nigrostriatal pathway decreases the response of GABA interneurons in the dorsal raphe nucleus to 5-HT(1A) receptor stimulation in the rat.

Neurochem. Int. 61(8) , 1344-56, (2012)

This study examined the firing rate and pattern of electrophysiologically and chemically identified GABA interneurons in the dorsal raphe nucleus (DRN), and role of 5-HT(1A) receptor agonist 8-OH-DPAT...

Electrophysiological and pharmacological properties of GABAergic cells in the dorsal raphe nucleus.

J. Physiol. Sci. 63(2) , 147-54, (2013)

The dorsal raphe nucleus (DRN) is the origin of the central serotonin [5-hydroxytryptamine (5-HT)] system and plays an important role in the regulation of many physiological functions such as sleep/ar...

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