Lanosterin

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Names

[ CAS No. ]:
79-63-0

[ Name ]:
Lanosterin

[Synonym ]:
Lanosterol
Lanster
MFCD00021108
Lanosta-8,24-dien-3-β-ol
Lanosterin
Kriptosterol
DUSOGEL
botalanbase
(3β)-Lanosta-8,24-dien-3-ol
Criptosterol
Lanosta-8,24-dien-3-ol, (3β)-
CRYPTOSTEROL
Kryptosterol
EINECS 201-214-9
(3β,5α)-4,4,14-trimethyl-Cholesta-8,24-dien-3-ol
Lanosta-8,24-dien-3β-ol (8CI)
Cholesta-8,24-dien-3-ol, 4,4,14-trimethyl-, (3β,5α)-
Lanosta-8,24-dien-3β-ol
(3β,20R)-Lanosta-8,24-dien-3-ol
(3S,5R,10S,13R,14R,17R)-4,4,10,13,14-Pentamethyl-17-[(2R)-6-methyl-5-hepten-2-yl]-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
lanosta-8,24-dien-3-ol, (3β,20R)-
Kryp-tosterol
(3b)-Lanosta-8,24-dien-3-ol
ISOCHOLESTEROL

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
498.9±44.0 °C at 760 mmHg

[ Melting Point ]:
137 °C

[ Molecular Formula ]:
C30H50O

[ Molecular Weight ]:
426.717

[ Flash Point ]:
221.1±20.7 °C

[ Exact Mass ]:
426.386169

[ PSA ]:
20.23000

[ LogP ]:
11.00

[ Appearance of Characters ]:
powder | white

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.530

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OE3360000
CHEMICAL NAME :
Lanosta-8,24-dien-3-ol, (3-beta)-
CAS REGISTRY NUMBER :
79-63-0
BEILSTEIN REFERENCE NO. :
2226449
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C30-H50-O
MOLECULAR WEIGHT :
426.80

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
1819 ug/kg
SEX/DURATION :
female 13 week(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - abortion
REFERENCE :
ZYZAEU Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. China) V.24- 1989- Volume(issue)/page/year: 27,528,1992

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
OE3360000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • lanosteryl acetate
  • 2,3-Oxidosqualene
  • CYCLOARTENOL
  • [(3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl] octanoate
  • 24(R,S)-3β-acetoxy-24,25-dihydroxy-5α-lanost-8-ene
  • 24-Ketolanosteryl acetate
  • 3β-acetoxy-(24E)-lanosta-8,24-dien-26-al

DownStream

  • Lanost-8-en-3-one
  • 32-hydroxylanosterol
  • FF-MAS

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Related Compounds

  • O-Acetyl-γ-lanosterin
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 3-Benzyl-4-methyl-7-(tetrazolidin-5-ylmethoxy)chromen-2-one
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 2,6-difluoro-N-(2-(3-(thiophen-2-yl)-1H-pyrazol-1-yl)ethyl)benzamide
  • tert-Butyl-DL-alanine