2-(Trimethylsilyl)thiazole

Names

[ Name ]:
2-(Trimethylsilyl)thiazole

[Synonym ]:
2-(Trimethylsilyl)thiazole
2-(Trimethylsilyl)-1,3-thiazole
trimethyl(1,3-thiazol-2-yl)silane
MFCD00066274
2-trimethylsilyl-1,3-thiazole
Thiazole, 2-(trimethylsilyl)-

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
174.7±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₆H₁₁NSSi

[ Molecular Weight ]:
157.309

[ Flash Point ]:
57.2±0.0 °C

[ Exact Mass ]:
157.038147

[ PSA ]:
41.13000

[ LogP ]:
2.09

[ Vapour Pressure ]:
1.6±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.487

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
IMMISCIBLE

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S23-S24/25-S26

[ RIDADR ]:
1993

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Thiazole
Chlorotrimethylsilane
2-Bromothiazole
lithium,2H-1,3-thiazol-2-ide

DownStream

5-Bromothiazole
5-BROMO-2-IODOTHIAZOLE
2-THIAZOLYL-2-THIENYL KETONE
2-Bromo-1-thiazol-2-yl-ethanone
Thiazole
Ethyl 2-chlorothiazole-5-carboxylate
ethyl 2-iodothiazole-5-carboxylate
2,5-BISTRIMETHYLSILANYLTHIAZOLE
Thiazole-5-boronic acid pinacol ester
2-(Tributylstannyl)-1,3-thiazole

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

A. Dondoni et al.

J. Org. Chem. 58 , 3196, (1993)

A. Dondoni, P. Merino

Organic Synth. 72 , 21, (1995)

Synthesis , 181, (1995)

2-(trimethylsilyl)thiazole-5-carbaldehyde
4-(TRIBUTYLSTANNYL)-2-(TRIMETHYLSILYL)THIAZOLE
5-(tributylstannyl)-2-(trimethylsilyl)thiazole
2-trimethylsilyl-1,3-thiazole-4-carbaldehyde
2-(((trimethylsilyl)oxy)methyl)benzo[d]thiazole
2-(trimethylsilyl)benzothiazole
Phosphonium, tributylethyl-, chloride
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
Toluene-4-sulfonicacid5-oxo-tetrahydro-pyran-2-ylmethylester
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
3-[(Azetidin-1-yl)methyl]piperidine
5-Quinolin-3-yl-[1,2,4]triazolo[1,5-a]pyrazin-2-ylamine
N,N-dimethyl-2-morpholino-4-oxo-8-(pyrrolidin-2-yl)-4H-chromene-6-carboxamide
1-[6-(2-Aminoethyl)-1,2,3,4-tetrahydroquinolin-1-yl]butan-1-one
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
2,2-Difluoro-1-(4-methoxy-3-methylphenyl)ethan-1-ol