4-(3,4-dichlorophenyl)-N-methyl-3,4-dihydro-2H-naphthalen-1-imine

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Names

[ CAS No. ]:
79560-20-6

[ Name ]:
4-(3,4-dichlorophenyl)-N-methyl-3,4-dihydro-2H-naphthalen-1-imine

[Synonym ]:
(1E)-4-(3,4-Dichlorophenyl)-N-methyl-3,4-dihydro-1(2H)-naphthalenimine
N-[(1E)-4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-ylidene]methanamine
Methanamine, N-[(1E)-4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenylidene]-
N-[(1E)-4-(3,4-Dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenylidene]methanamine
N-[(1E)-4-(3,4-Dichlorphenyl)-3,4-dihydronaphthalen-1(2H)-yliden]methanamin
N-(4(3,4-dichlorophenyl)-3,4-dihydro-1(2H)naphthalidene) methanamine; (intermediate for sertraline)

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
390.5±42.0 °C at 760 mmHg

[ Melting Point ]:
243-247ºC

[ Molecular Formula ]:
C17H15Cl2N

[ Molecular Weight ]:
304.214

[ Flash Point ]:
190.0±27.9 °C

[ Exact Mass ]:
303.058167

[ PSA ]:
12.36000

[ LogP ]:
4.79

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.619

Safety Information

[ Safety Phrases ]:
S22-S24/25

[ WGK Germany ]:
3

[ RTECS ]:
QJ0352070

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-(3,4-Dichlorophenyl)tetralone
  • methylamine
  • (3,4-dichlorophenyl)(phenyl)methanone
  • 4-(3,4-dichlorophenyl)-4-phenylbut-3-enoic acid
  • 3-(ethoxycarbonyl)-4-(3,4-dichlorophenyl)-4-phenylbut-3-enoic acid
  • 4-(3,4-DICHLOROPHENYL)-4-PHENYLBUTYRIC ACID
  • 1,2-Dichlorobenzene
  • 1-Naphthalenol

DownStream

  • Sertraline
  • cis-(1S,4S)-N-methyl-(3-chlorophenyl)-1,2,3,4-tetrahydro-1-naphtalenamine
  • 1-Naphthalenamine, 4-(4-chlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, (1S,4S)
  • 4-(3,4-Dichlorophenyl)tetralone
  • trans-(1S,4R)-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine
  • (1R,4R)-Sertraline HCl
  • trans-(1R,4S)-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine
  • cis-sertraline
  • Rac-trans-Sertraline
  • 1-Naphthalenamine,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • Tert-butyl 5-amino-3-bromo-2-hydroxybenzoate
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide