Linifanib (ABT-869)

Suppliers

Names

[ CAS No. ]:
796967-16-3

[ Name ]:
Linifanib (ABT-869)

[Synonym ]:
Linifanib
S1003_Selleck
Kinome_532
ABT 869
ABT-869

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
542.2±50.0 °C at 760 mmHg

[ Melting Point ]:
180-183ºC (dec.)

[ Molecular Formula ]:
C21H18FN5O

[ Molecular Weight ]:
375.399

[ Flash Point ]:
281.7±30.1 °C

[ Exact Mass ]:
375.149536

[ PSA ]:
95.83000

[ LogP ]:
4.34

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.766

[ Storage condition ]:
-20?C Freezer

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Iodo-1H-indazol-3-amine
  • N-(2-Fluoro-5-methylphenyl)-N'-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea
  • 4-chloro-1H-indazol-3-amine
  • 3-Amino-4-fluorotoluene
  • 2-Fluoro-6-iodobenzonitrile
  • 4-AMinophenylboronic acid pinacol ester
  • N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea monohydrate

DownStream

Related Compounds

  •
  • (Rac)-ABT-202 dihydrochloride
  • Veliparib (ABT-888)
  • Cethromycin
  • Venetoclax (ABT-199)
  • AscroliMus(ABT-281)
  • 4-Chlorophenyl 2,4,5-trimethylbenzene-1-sulfonate
  • 4-Ethylphenyl 5-chloro-2-methoxybenzenesulfonate
  • 4-Ethylphenyl 5-bromo-2-methoxybenzenesulfonate
  • 2-((2-Chlorophenyl)thio)-1-(2,5-dimethyl-1h-pyrrol-3-yl)ethan-1-one
  • 1-(Methylsulfonyl)-4-[2-(2-pyridinyl)ethyl]piperazine
  • N-(2-(3,5-dimethylphenoxy)ethyl)-2-nitrobenzenesulfonamide
  • N-(6-chloroquinolin-4-yl)-3-(cyclopropylsulfamoyl)benzamide
  • 2-(1-Oxopropoxy)-1-naphthalenecarboxaldehyde
  • 2-((1-(2,5-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)ethanol
  • Ethyl 4-amino-6-[4-(diethylsulfamoyl)benzamido]quinoline-3-carboxylate
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