5-chloro-3-(4-methoxyphenyl)-1H-benzimidazol-2-one

Names

[ CAS No. ]:
79759-69-6

[ Name ]:
5-chloro-3-(4-methoxyphenyl)-1H-benzimidazol-2-one

Chemical & Physical Properties

[ Density]:
1.358g/cm3

[ Molecular Formula ]:
C14H11ClN2O2

[ Molecular Weight ]:
274.70200

[ Exact Mass ]:
274.05100

[ PSA ]:
47.28000

[ LogP ]:
3.39310

[ Index of Refraction ]:
1.633

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DE2275915
CHEMICAL NAME :
2H-Benzimidazol-2-one, 1,3-dihydro-6-chloro-1-(4-methoxyphenyl)-
CAS REGISTRY NUMBER :
79759-69-6
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H11-Cl-N2-O2
MOLECULAR WEIGHT :
274.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 16,321,1981

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 5-chloro-3-(4-hydroxyphenyl)-1H-benzimidazol-2-one
  • 5-chloro-3-(4-chlorophenyl)-1H-benzimidazol-2-one
  • 1,3-Dihydro-6-chloro-1-(4-(phenylmethoxy)phenyl)-2H-benzimidazol-2-one
  • 5-chloro-3-(4-methoxyphenyl)-1-methylbenzimidazol-2-one
  • 5-chloro-3-(2-chlorophenyl)-1H-benzimidazol-2-one
  • 5-chloro-3-(4-chlorophenyl)-1-methyl-benzoimidazol-2-one
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • (E)-N-(5-(2,4-dimethylthiazol-5-yl)-1,3,4-oxadiazol-2-yl)-3-(thiophen-2-yl)acrylamide
  • (5-{2-[1-(3,4,5-Trichlorobenzyl)-1H-1,2,3-triazol-4-yl]-1,3-thiazol-5-yl}-2H-tetrazolyl)acetic acid
  • 4-Cyclobutylpyrimidin-2-amine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde