Idazoxan Hydrochloride

Names

[ CAS No. ]:
79944-56-2

[ Name ]:
Idazoxan Hydrochloride

[Synonym ]:
Idazoxan Hydrochloride
Melanotan II
IdazoxanHCl

Chemical & Physical Properties

[ Boiling Point ]:
397ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₃ClN₂O₂

[ Molecular Weight ]:
240.68600

[ Flash Point ]:
193.9ºC

[ Exact Mass ]:
240.06700

[ PSA ]:
42.85000

[ LogP ]:
1.39450

MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
22

[ Safety Phrases ]:
7

[ RIDADR ]:
UN 2811 6.1/PG 3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

The timing of dopamine- and noradrenaline-mediated transmission reflects underlying differences in the extent of spillover and pooling.

J. Neurosci. 34(22) , 7645-56, (2014)

Metabotropic transmission typically occurs through the spillover activation of extrasynaptic receptors. This study examined the mechanisms underlying somatodendritic dopamine and noradrenaline transmi...

Mirabegron relaxes urethral smooth muscle by a dual mechanism involving β3 -adrenoceptor activation and α1 -adrenoceptor blockade.

Br. J. Pharmacol. 173 , 415-28, (2016)

This article is commented on by Michel, M. C., pp. 429-430 of this issue. To view this commentary visit http://dx.doi.org/10.1111/bph.13379.Mirabegron is the first β3 -adrenoceptor agonist approved fo...

Chemical stimulation of the ST36 acupoint reduces both formalin-induced nociceptive behaviors and spinal astrocyte activation via spinal alpha-2 adrenoceptors

Brain Res. Bull. 86(5-6) , 412-21, (2011)

Highlights ► DBV's anti-nociceptive effect involves suppression of spinal astrocyte activation. ► DBV-induced astrocyte inhibition is mediated by spinal alpha-2A and alpha-2C adrenoceptors. ► Astrocyt...