4,4'-Dichlorodiphenyl sulfone

Suppliers

Names

[ CAS No. ]:
80-07-9

[ Name ]:
4,4'-Dichlorodiphenyl sulfone

[Synonym ]:
EINECS 201-247-9
1,1'-Sulfonylbis(4-chlorobenzene)
Benzene, 1,1'-sulfonylbis[4-chloro-
4,4'-Dichlorodiphenylsulfone
Bis(4-chlorophenyl) sulfone
1-chloro-4-(4-chlorophenyl)sulfonylbenzene
MFCD00000619
4,4'-Dichlorodiphenyl sulfone

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
419.9±0.0 °C at 760 mmHg

[ Melting Point ]:
143-146 °C(lit.)

[ Molecular Formula ]:
C₁₂H₈Cl₂O₂S

[ Molecular Weight ]:
287.162

[ Flash Point ]:
211.2±24.6 °C

[ Exact Mass ]:
285.962219

[ PSA ]:
42.52000

[ LogP ]:
4.20

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.610

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
<0.1 g/100 mL at 20 ºC

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WR3450000

CHEMICAL NAME :: Sulfone, bis(p-chlorophenyl)

CAS REGISTRY NUMBER :: 80-07-9

BEILSTEIN REFERENCE NO. :: 2052955

LAST UPDATED :: 199712

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C12-H8-Cl2-O2-S

MOLECULAR WEIGHT :: 287.16

WISWESSER LINE NOTATION :: GR DSWR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7500 mg/kg

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0533718

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 24 gm/kg

TOXIC EFFECTS :: Behavioral - tremor

REFERENCE :: HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 29,1317,1946 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 364 mg/kg/26W-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Liver - liver function tests impaired

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 47(2),84,1982 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 10 ppm JAN 1993

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25-S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
WR3450000

[ HS Code ]:
29309070

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Chlorobenzene
Bis(4-chlorophenyl) sulfoxide
4-Chlorobenzenesulfonyl chloride
4-Chlorobenzenesulfonic acid
Sodium 4-chlorobenzene sulfinate
bis(4-chlorophenyl)iodanium,bromide
bis(4-chlorophenyl) sulfide
4,4'-Sulfonyldiphenol
Methyl 4-chlorobenzenesulfonate

DownStream

4,4'-Sulfonyldiphenol
2,4-BPS
Benzenamine,4,4'-sulfonylbis[2-nitro-
1,4-Dichlorobenzene
Sulfenone
Diphenylsulfid
4,4'-PCB
Chlorobenzene
Benzenamine,4,4'-sulfonylbis[2-nitro-N-phenyl-
4,4'-Diaminodiphenylsulfone

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Enantiomeric specificity of methylsulfonyl-PCBs and distribution of bis(4-chlorophenyl) sulfone, PCB, and DDE methyl sulfones in grey seal tissues.

Environ. Sci. Technol. 38(19) , 4950-5, (2004)

PCB methyl sulfones (MeSO2-PCBs) are lipophilic PCB metabolites of which five of the environmentally relevant meta/para pairs are chiral (i.e., exist as atropisomeric pairs). Methylsulfonyl-DDE (MeSO2...

Temporal trend of bis(4-chlorophenyl) sulfone, methylsulfonyl-DDE and -PCBs in Baltic guillemot (Uria aalge) egg 1971-2001--a comparison to 4,4'-DDE and PCB trends.

Environ. Pollut. 141(2) , 226-37, (2006)

The dynamics of organohalogen contaminants and their metabolites are best studied over time by analysis of biota at high trophic levels. In this study, time trends, 1971-2001, of bis(4-chlorophenyl) s...

Immobilization of Mucor miehei Lipase onto Macroporous Aminated Polyethersulfone Membrane for Enzymatic Reactions.

Membranes (Basel.) 2 , 198-213, (2014)

Immobilization of enzymes is one of the most promising methods in enzyme performance enhancement, including stability, recovery, and reusability. However, investigation of suitable solid support in en...

3,3'-dinitro-4,4'-dichlorodiphenyl sulfone
3,3'-Diamino-4,4'-dichlorodiphenyl sulfone
4-[(3,4-Dichlorophenyl)sulfonyl]aniline
5,5-Dichloro-2,2-dihydroxydiphenyl sulfone
bis(4-chlorophenyl) disulfide
2-(4-Chlorophenoxy)-5-chlorobenzoic acid
3-(2,3-Dihydro-1H-indol-1-yl)butanol-1-ol
2-(4-(3-Methoxyphenyl)piperazin-1-yl)ethan-1-ol
3-[Cyclopropyl(methyl)amino]propan-1-ol
N-(3-methoxybenzyl)-N-methyl-2-[1-(1-naphthylmethyl)-3-oxo-2-piperazinyl]acetamide
4-(2-hydroxyethyl)-3,4-dihydro-2H-1,4-benzoxazin-3-one
5-bromo-1-(3-hydroxypropyl)pyridin-2(1H)-one
4-(1H-Pyrazol-1-yl)butan-1-ol
3-(4-Hydroxybutyl)-1,3-thiazolidine-2,4-dione
3-(4-Nitro-1h-imidazol-1-yl)propan-1-ol
3-(4-Hydroxybutyl)-1,3-oxazolidin-2-one

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.