2-Bromobutyric acid

Names

[ CAS No. ]:
80-58-0

[ Name ]:
2-Bromobutyric acid

[Synonym ]:
2-Bromobutanoic acid
EINECS 201-294-5
2-Bromobutyric acid
MFCD00004216
Butanoic acid, 2-bromo-

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
216.6±13.0 °C at 760 mmHg

[ Melting Point ]:
−4 °C(lit.)

[ Molecular Formula ]:
C₄H₇BrO₂

[ Molecular Weight ]:
167.001

[ Flash Point ]:
84.8±19.8 °C

[ Exact Mass ]:
165.962936

[ PSA ]:
37.30000

[ LogP ]:
1.39

[ Vapour Pressure ]:
0.1±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.493

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
66 g/L (20 ºC)

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R22;R34

[ Safety Phrases ]:
S26-S28A-S24-S16-S9-S2-S45-S36/37/39

[ RIDADR ]:
3265

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
29349990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Butyric Acid
2-Aminobutanoic acid
3-Bromo-4-methoxyphenyl (S)-2-bromobutanoate
Butanoic acid silver(I) salt
Methyl 2-bromobutyrate
Butanoic anhydride
L(+)-2-Aminobutyric acid
(R)-2-BROMOBUTANOIC ACID
Bromine

DownStream

Butanoic acid,2-methylene-
DL-Ethyl 2-bromobutyrate
Crotonic acid
2,4-diethyl-3-oxa-glutaric acid
(±)-2-hydroxybutyric acid
Rhodanine, 5-ethyl-3-phenyl-
2-bromobutan-1-ol
Thiazole
2-Aminobutanoic acid
Butanamide

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Articles

Stable chlorine isotope analysis of chlorinated acetic acids using gas chromatography/quadrupole mass spectrometry.

Rapid Commun. Mass Spectrom. 29 , 2341-8, (2015)

The environmental occurrence of chlorinated acetic acids (CAAs) has been extensively studied, but the sources and transport are still not yet fully understood. A promising approach for source apportio...

Synthesis and chromatographic properties of S-(1-carboxyethyl)-L-cysteine and S-(1-carboxypropyl)-L-cysteine.

Ital. J. Biochem. 36(1) , 1-7, (1987)

Details are reported for the synthesis of S-(1-carboxyethyl)-L-cysteine (1-CEC) and S-(1-carboxypropyl)-L-cysteine (1-CPC) from cysteine and 2-bromopropionic acid or 2-bromobutyric acid, respectively....

Selective reduction of fatty acid oxidation in colonocytes: correlation with ulcerative colitis.

Lipids 25(10) , 646-52, (1990)

Attempts were made to define which fatty acid (2:0 to 18:1) was optimally oxidized by isolated colonocytes (colonic epithelial cells) and to select inhibitors of fatty acid oxidation which would be an...