AT 1902

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Names

[ CAS No. ]:
80155-82-4

[ Name ]:
AT 1902

[Synonym ]:
Nitrilotri-essigsaeure-trihydrazid
Tris-carboxymethyl-aminoxid
nitrilotriacetic acid N-oxide
Nitrilotriessigsaeure N-oxid
nitrilotri-acetic acid trihydrazide
Triglykolamidsaeuretrihydrazid

Chemical & Physical Properties

[ Molecular Formula ]:
C6H15N7O3

[ Molecular Weight ]:
233.22800

[ Exact Mass ]:
233.12400

[ PSA ]:
168.60000

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AJ0600000
CHEMICAL NAME :
Acetic acid, nitrilotri-, trihydrazide
CAS REGISTRY NUMBER :
80155-82-4
BEILSTEIN REFERENCE NO. :
1714871
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C6-H15-N7-O3
MOLECULAR WEIGHT :
233.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1343 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KHTPBU Kexue Tongbao (Foreign Language Edition). Science Bulletin. (Scientific and Technical Book Service, Ltd., POB 197, London, WC2N 4DE, UK) V.17, 1966; V.25- 1980- Suspended 1966-79. Volume(issue)/page/year: 27,787,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1736 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KHTPBU Kexue Tongbao (Foreign Language Edition). Science Bulletin. (Scientific and Technical Book Service, Ltd., POB 197, London, WC2N 4DE, UK) V.17, 1966; V.25- 1980- Suspended 1966-79. Volume(issue)/page/year: 27,787,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
105 mg/kg/7D-I
TOXIC EFFECTS :
Gastrointestinal - nausea or vomiting Gastrointestinal - other changes Related to Chronic Data - death
REFERENCE :
KHTPBU Kexue Tongbao (Foreign Language Edition). Science Bulletin. (Scientific and Technical Book Service, Ltd., POB 197, London, WC2N 4DE, UK) V.17, 1966; V.25- 1980- Suspended 1966-79. Volume(issue)/page/year: 27,787,1982
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
70 mg/kg/7D-I
TOXIC EFFECTS :
Gastrointestinal - nausea or vomiting Gastrointestinal - other changes Related to Chronic Data - death
REFERENCE :
KHTPBU Kexue Tongbao (Foreign Language Edition). Science Bulletin. (Scientific and Technical Book Service, Ltd., POB 197, London, WC2N 4DE, UK) V.17, 1966; V.25- 1980- Suspended 1966-79. Volume(issue)/page/year: 27,787,1982
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
87500 ug/kg/7D-I
TOXIC EFFECTS :
Gastrointestinal - other changes Related to Chronic Data - death
REFERENCE :
KHTPBU Kexue Tongbao (Foreign Language Edition). Science Bulletin. (Scientific and Technical Book Service, Ltd., POB 197, London, WC2N 4DE, UK) V.17, 1966; V.25- 1980- Suspended 1966-79. Volume(issue)/page/year: 27,787,1982

Synthetic Route

Precursor & DownStream

Precursor

  • 2,2',2''-Nitrilotriacetic acid triethyl ester
  • nitrilotriacetic acid

DownStream


Related Compounds

  • 2-[bis(2-hydrazinyl-2-oxoethyl)amino]acetohydrazide
  • AT-101
  • AT-9283 L-lactate
  • AT-273
  • AT-511
  • AT 9283 (L-GLUTAMIC ACID SALT)
  • (2-tert-butyl-1H-imidazol-5-yl)methanamine
  • 2,3-Diethyl 5,8-dimethoxy-2,3-quinoxalinedicarboxylate
  • (2-(3-Bromophenyl)-1H-imidazol-5-YL)methanamine
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-[2-[formyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]phenyl]-4-oxobutanoic acid
  • (2-(4-Bromophenyl)-1H-imidazol-5-YL)methanamine
  • 2-(6-bromopyridin-3-yl)oxy-N-methylacetamide
  • (2-(3-Methoxyphenyl)-1H-imidazol-5-YL)methanamine
  • (2-(3-Fluorophenyl)-1H-imidazol-5-YL)methanamine
  • (2-(4-Methoxyphenyl)-1H-imidazol-5-YL)methanamine
  • 2-tert-butyl-5-(chloromethyl)-1H-imidazole
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