Silybin

Suppliers

Names

[ Name ]:
Silybin

[Synonym ]:
(2R,3R)-2-[2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one
silibin
silybin
Silybin
Silybin A,B (mixture)

Chemical & Physical Properties

[ Melting Point ]:
152-153°C

[ Molecular Formula ]:
C₂₅H₂₂O₁₀

[ Molecular Weight ]:
482.43600

[ Exact Mass ]:
482.12100

[ PSA ]:
155.14000

[ LogP ]:
2.36270

[ Storage condition ]:
Refrigerator

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
DJ2981770

Articles

The in-vitro effect of complementary and alternative medicines on cytochrome P450 2C9 activity.

J. Pharm. Pharmacol. 66(9) , 1339-46, (2014)

The aim of this study is to establish the inhibitory effects of 14 commonly used complementary and alternative medicines (CAM) on the metabolism of cytochrome P450 2C9 (CYP2C9) substrates 7-methoxy-4-...

Engineered silybin nanoparticles educe efficient control in experimental diabetes.

PLoS ONE 9(7) , e101818, (2014)

Silybin, is one imminent therapeutic for drug induced hepatotoxicity, human prostate adenocarcinoma and other degenerative organ diseases. Recent evidences suggest that silybin influences gluconeogene...

Isolation and purification of diastereoisomeric flavonolignans from silymarin by binary-column recycling preparative high-performance liquid chromatography.

J. Sep. Sci. 37(17) , 2300-6, (2014)

Silymarin extracted from Silybum marianum (L.) Gaertn consists of a large number of flavonolignans, of which diastereoisomeric flavonolignans including silybin A and silybin B, and isosilybin A and is...

Silybin
Silybin
Silybin
Silybin
Silybin b2
silybin dihemisuccinate
sodium 5-(2-ethoxy-2-oxoacetyl)-1-methyl-1H-pyrrole-3-sulfinate
tert-butyl N-[3-methoxy-4-(2-sulfanylethyl)phenyl]carbamate
2-Fluoro-4-(3-sulfanylpropyl)phenol
Sodium 1-benzylpyrrolidine-3-sulfinate
2-(3-Fluoro-4-hydroxyphenyl)butanedioic acid
1-(Bromomethyl)-3-oxaspiro[bicyclo[3.1.0]hexane-2,3'-thiolane]
(2-Cyclopentyl-4,5-dimethylfuran-3-yl)methanol
1-[(tert-butoxy)carbonyl]-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}(4,4,4-trifluorobutyl)amino)piperidine-4-carboxylic acid
1-[(tert-butoxy)carbonyl]-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}[2-(1-methoxycyclobutyl)ethyl]amino)azetidine-3-carboxylic acid
2-methyl-5-(1H-1,2,4-triazol-1-yl)pentan-2-ol

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