CARBAMIC ACID, (2-CHLOROETHYL)NITROSO-, 2,5-DIOXO-1-PYRROLIDINYL ESTER

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Names

[ CAS No. ]:
80354-49-0

[ Name ]:
CARBAMIC ACID, (2-CHLOROETHYL)NITROSO-, 2,5-DIOXO-1-PYRROLIDINYL ESTER

[Synonym ]:
ICIG 1734
N'-hydroxysuccinimide N-(2-chloroethyl)-N-nitrosocarbamate
N-(2-chloroethyl)-N-nitrosocarbamic acid N-hydroxypyrrolidine-2,5-dione ester
N-(2-chloroethyl)-N-nitrosocarbamic acid N'-hydroxysuccinimide ester
N-nitroso-2-chloroethyl-carbamic acid N-hydroxysuccinimide ester
N-(Chloro-2 ethyl) N-nitrosocarbamate de succinimidyle [French]
N-<N-(2-Chloroethyl)-N-nitrosocarbamoyloxy>succinimide
CARBAMIC ACID,(2-CHLOROETHYL)NITROSO-,2,5-DIOXO-1-PYRROLIDINYL ESTER
N-(2-chloroethyl)-N-nitrosocarbamic acid succinimido ester
N'-hydroxysuccinimide-N-(2-chloroethyl)nitrosocarbamate
(2-Chloroethyl)nitrosocarbamic acid 2,5-dioxo-1-pyrrolidinyl ester

Chemical & Physical Properties

[ Density]:
1.68g/cm3

[ Boiling Point ]:
347.1ºC at 760 mmHg

[ Molecular Formula ]:
C7H8ClN3O5

[ Molecular Weight ]:
249.60900

[ Flash Point ]:
163.7ºC

[ Exact Mass ]:
249.01500

[ PSA ]:
96.35000

[ LogP ]:
0.34710

[ Index of Refraction ]:
1.628

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2,5-dioxopyrrolidin-1-yl) N-(2-chloroethyl)carbamate
  • N,N'-Disuccinimidyl carbonate

DownStream

  • tert-butyl N-[(5S)-5-amino-6-[(2S)-2-[[(2S)-1-[[(2S)-1-[2-chloroethyl(nitroso)carbamoyl]pyrrolidine-2-carbonyl]amino]-3-methyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-6-oxohexyl]carbamate
  • (2S)-2-N-[(2S)-2-[[(2S)-1-[(2S)-2-amino-6-formamidohexanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]-1-N-(2-chloroethyl)-1-N-nitrosopyrrolidine-1,2-dicarboxamide
  • Lomustine
  • 2-((3-chloroethyl)-3-nitrosoureido)glucopyranose
  • 1-(2-chloroethyl)-3-[2-[2-[(2-chloroethyl-nitroso-carbamoyl)amino]ethy ldisulfanyl]ethyl]-1-nitroso-urea
  • 2-[(2-chloroethyl-nitroso-carbamoyl)amino]acetamide