N,1-bis(2-chlorophenyl)-2,6-dimethyl-4-oxopyridine-3-carboxamide

Names

[ CAS No. ]:
80357-43-3

[ Name ]:
N,1-bis(2-chlorophenyl)-2,6-dimethyl-4-oxopyridine-3-carboxamide

Chemical & Physical Properties

[ Density]:
1.376g/cm3

[ Boiling Point ]:
548.8ºC at 760 mmHg

[ Molecular Formula ]:
C20H16Cl2N2O2

[ Molecular Weight ]:
387.25900

[ Flash Point ]:
285.7ºC

[ Exact Mass ]:
386.05900

[ PSA ]:
54.59000

[ LogP ]:
5.39740

[ Index of Refraction ]:
1.656

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QS4470100
CHEMICAL NAME :
Nicotinamide, 1,4-dihydro-N,1-bis(o-chlorophenyl)-2,6-dimethyl-4-ox o-
CAS REGISTRY NUMBER :
80357-43-3
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H16-Cl2-N2-O2
MOLECULAR WEIGHT :
387.28
WISWESSER LINE NOTATION :
T6N DVJ AR BG& B1 CVMR BG& F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
562 mg/kg
TOXIC EFFECTS :
Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 25,131,1982

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • (E)-1-(5-(2,4-diaminopyrimidin-5-yloxy)-4-isopropyl-2-methoxyphenyl)-3-(dimethylamino)prop-2-en-1-one
  • (2-Isopropyl-4-methoxy-5-thiazol-4-yl-phenoxy)-acetonitrile
  • 5-(2-Isopropyl-4-methoxy-5-methyl-phenoxy)-N4-phenyl-pyrimidine-2,4-diamine
  • 4-Chloro-5-(2-isopropyl-4,5-dimethoxy-benzyl)-2-methylsulfanyl-pyrimidine
  • [5-(2,4-Diamino-pyrimidin-5-yloxy)-4-isopropyl-2-methoxy-phenyl]-urea
  • 2-Isopropyl-4-methoxy-5-(oxazol-4-yl)phenyl 4-methylbenzenesulfonate
  • [2-(4-Iodo-imidazol-1-yl)ethyl]carbamic acid tert-butyl ester
  • 7-Isopropyl-4-methyl-benzooxazol-6-ol
  • (5-Chloro-2-isopropyl-4-methoxy-phenoxy)-acetonitrile
  • 2-Amino-6-methylpyrimidine-4-carbaldehyde
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