L-Glutamic acid, N-[4-[[ (2,4-diaminopyrido[2, 3-d]pyrimidin-6-yl)methyl]amino]benzoyl]-, diethyl ester

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Names

[ CAS No. ]:
80360-08-3

[ Name ]:
L-Glutamic acid, N-[4-[[ (2,4-diaminopyrido[2, 3-d]pyrimidin-6-yl)methyl]amino]benzoyl]-, diethyl ester

[Synonym ]:
diethyl N-(4-{[(2,4-diaminopyrido[2,3-d]pyrimidin-6-yl)methyl]amino}benzoyl)-L-glutamate
diethyl (2S)-2-[[4-[(2,4-diaminopyrido[2,3-d]pyrimidin-6-yl)methylamino]benzoyl]amino]pentanedioate
L-Glutamic acid,4-diaminopyrido[2,3-d]pyrimidin-6-yl)methyl]amino]benzoyl]-,diethyl ester
N-[4-[[(2,4-Diaminopyrido[2,3-d]pyrimidin-6-yl)methyl]-amino]benzoyl]-L-glutamic Acid Diethyl Ester
diethyl N-<p-<<(2,4-diaminopyrido<2,3-d>pyrimidin-6-yl)methyl>amino>benzoyl>-L-glutamate

Chemical & Physical Properties

[ Density]:
1.347g/cm3

[ Molecular Formula ]:
C24H29N7O5

[ Molecular Weight ]:
495.53100

[ Exact Mass ]:
495.22300

[ PSA ]:
184.44000

[ LogP ]:
3.43240

[ Index of Refraction ]:
1.656

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Diethyl N-(4-aminobenzoyl)-L-glutamate
  • 2,4-diaminopyrido[2,3-d]pyrimidine-6-carbonitrile
  • 2,4-diaminopyrido[2,3-d]pyrimidine-6-carbaldehyde
  • 7-chloro-6-cyano-1,3-bis(methoxymethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione
  • 7-hydroxy-1,3-bis(methoxymethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
  • sodium carbonate

DownStream

  • 5-Deazamethotrexate
  • 2-[[4-[(9-amino-7-oxo-2,8,10-triazabicyclo[4.4.0]deca-2,4,8,11-tetraen-4-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic acid

Related Compounds

  • 3-(2-{[(Tert-butoxy)carbonyl]amino}-5-fluorophenyl)-2,2-dimethylpropanoic acid
  • 1-[(cyclohexyloxy)methyl]-5-methyl-1H-pyrazol-4-amine
  • 1-{[1-(methoxymethyl)cyclobutyl]methyl}-5-methyl-1H-pyrazol-4-amine
  • 1-[(cyclohexyloxy)methyl]-1H-1,2,3-triazol-4-amine
  • (4-Phenylpiperidin-4-yl)methanesulfonyl fluoride
  • 6-(4-Bromo-3-(methoxymethoxy)phenyl)-8-fluoro-2-methylimidazo[1,2-a]pyridine
  • 7-(7-methyl-2,3-dihydro-1H-indol-4-yl)-1H-indole
  • 2-{[5-(2-bromopyridin-3-yl)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-octahydro-1H-isoindol-5-yl]oxy}acetic acid
  • (9H-fluoren-9-yl)methyl 4-{[3-azido-5-(fluorosulfonyl)-2,4,6-trimethylphenyl]methyl}piperazine-1-carboxylate
  • 5-(Aminomethyl)furan-2-sulfonyl fluoride
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