L-Glutamic acid, N-[4-[[ (2,4-diaminopyrido[2, 3-d]pyrimidin-6-yl)methyl]amino]benzoyl]-, diethyl ester

Suppliers

Names

[ CAS No. ]:
80360-08-3

[ Name ]:
L-Glutamic acid, N-[4-[[ (2,4-diaminopyrido[2, 3-d]pyrimidin-6-yl)methyl]amino]benzoyl]-, diethyl ester

[Synonym ]:
diethyl N-(4-{[(2,4-diaminopyrido[2,3-d]pyrimidin-6-yl)methyl]amino}benzoyl)-L-glutamate
diethyl (2S)-2-[[4-[(2,4-diaminopyrido[2,3-d]pyrimidin-6-yl)methylamino]benzoyl]amino]pentanedioate
L-Glutamic acid,4-diaminopyrido[2,3-d]pyrimidin-6-yl)methyl]amino]benzoyl]-,diethyl ester
N-[4-[[(2,4-Diaminopyrido[2,3-d]pyrimidin-6-yl)methyl]-amino]benzoyl]-L-glutamic Acid Diethyl Ester
diethyl N-<p-<<(2,4-diaminopyrido<2,3-d>pyrimidin-6-yl)methyl>amino>benzoyl>-L-glutamate

Chemical & Physical Properties

[ Density]:
1.347g/cm3

[ Molecular Formula ]:
C24H29N7O5

[ Molecular Weight ]:
495.53100

[ Exact Mass ]:
495.22300

[ PSA ]:
184.44000

[ LogP ]:
3.43240

[ Index of Refraction ]:
1.656

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Diethyl N-(4-aminobenzoyl)-L-glutamate
  • 2,4-diaminopyrido[2,3-d]pyrimidine-6-carbonitrile
  • 2,4-diaminopyrido[2,3-d]pyrimidine-6-carbaldehyde
  • 7-chloro-6-cyano-1,3-bis(methoxymethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione
  • 7-hydroxy-1,3-bis(methoxymethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carbonitrile
  • sodium carbonate

DownStream

  • 5-Deazamethotrexate
  • 2-[[4-[(9-amino-7-oxo-2,8,10-triazabicyclo[4.4.0]deca-2,4,8,11-tetraen-4-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic acid

Related Compounds

  • tert-butyl 3-(hydroxymethyl)-3-(1H-pyrazol-1-yl)azetidine-1-carboxylate
  • 6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpyridine-2-carboxylic acid
  • 4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-fluorophenyl)-1,2-thiazole-5-carboxylic acid
  • 1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)phenyl]-1H-1,2,3-triazole-4-carboxylic acid
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(4-methylphenyl)thiophene-2-carboxylic acid
  • 2-chloro-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)benzoic acid
  • 2-[6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1H-indazol-1-yl]acetic acid
  • 5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-6-methylpyrazine-2-carboxylic acid
  • 2-{[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)naphthalen-1-yl]oxy}acetic acid
  • 2-[2-chloro-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)phenoxy]acetic acid