ethyl 4-(4-chloro-2-fluorophenyl)-4-hydroxybut-2-ynoate

Names

[ CAS No. ]:
803732-73-2

[ Name ]:
ethyl 4-(4-chloro-2-fluorophenyl)-4-hydroxybut-2-ynoate

[Synonym ]:
2-Butynoic acid,4-(4-chloro-2-fluorophenyl)-4-hydroxy-,ethyl ester

Chemical & Physical Properties

[ Molecular Formula ]:
C12H10ClFO3

[ Molecular Weight ]:
256.65700

[ Exact Mass ]:
256.03000

[ PSA ]:
46.53000

[ LogP ]:
2.07900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Chloro-2-fluorobenzaldehyde
  • Ethyl propiolate

DownStream

Related Compounds

  • 2,6-difluoro-N-(4-{[6-(3-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]amino}phenyl)benzamide
  • 2-chloro-6-fluoro-N-(4-{[6-(3-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]amino}phenyl)benzamide
  • N-(4-{[6-(3-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]amino}phenyl)-2-(trifluoromethyl)benzamide
  • N-(4-{[6-(3-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]amino}phenyl)-3-(trifluoromethyl)benzamide
  • N-(4-{[6-(3-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]amino}phenyl)-4-(trifluoromethyl)benzamide
  • N-(4-{[6-(3-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]amino}phenyl)-2-phenylacetamide
  • 2-(4-methoxyphenyl)-N-(4-{[6-(3-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]amino}phenyl)acetamide
  • N-(4-{[6-(3-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]amino}phenyl)thiophene-2-carboxamide
  • N-(4-{[6-(3-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]amino}phenyl)-2H-1,3-benzodioxole-5-carboxamide
  • N-(4-{[6-(3-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]amino}phenyl)furan-2-carboxamide