N-Trifluoroacetyladriamycin-14-O-hemiadipate

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Names

[ CAS No. ]:
80787-29-7

[ Name ]:
N-Trifluoroacetyladriamycin-14-O-hemiadipate

[Synonym ]:
Ad143
N-(trifluoroacetyl)adriamycin 14-O-hemiadipate
N-trifluoroacetyldoxorubicin 14-O-hemiadipate

Chemical & Physical Properties

[ Density]:
1.6g/cm3

[ Boiling Point ]:
952.5ºC at 760 mmHg

[ Molecular Formula ]:
C35H36F3NO15

[ Molecular Weight ]:
767.65300

[ Flash Point ]:
529.9ºC

[ Exact Mass ]:
767.20400

[ PSA ]:
252.52000

[ LogP ]:
2.30790

[ Index of Refraction ]:
1.631

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QI9429000
CAS REGISTRY NUMBER :
80787-29-7
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C35-H36-F3-N-O15
MOLECULAR WEIGHT :
767.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
13 umol/L
REFERENCE :
PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 27,239,1986

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • sodium,6-hydroxy-6-oxohexanoate
  • N-(trifluoroacetyl)-14-bromodaunorubicin

DownStream

Related Compounds

  • Valrubicin
  • N-O-NITROPHENYLSULFENYL-L-TYROSINE DI(CYCLOHEXYL)AMMONIUM SALT
  • N-O-NITROPHENYLSULFENYL-L-TRYPTOPHAN DI(CYCLOHEXYL)AMMONIUM SALT
  • N,O-Diacetyl-L-tyrosine
  • N,O-Bis(trifluoroacetyl)-L-tyrosine butyl ester
  • N,O-Ditosyl D-Phenylalaninol