3-Methoxy-4-Nitrobenzyl Alcohol

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Names

[ CAS No. ]:
80866-88-2

[ Name ]:
3-Methoxy-4-Nitrobenzyl Alcohol

[Synonym ]:
EINECS 279-593-5
Benzyl alcohol, 3-methoxy-4-nitro-
(3-Methoxy-4-nitrophenyl)methanol
Benzenemethanol, 3-methoxy-4-nitro-
MFCD00007098

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
367.3±27.0 °C at 760 mmHg

[ Melting Point ]:
95-97ºC(lit.)

[ Molecular Formula ]:
C8H9NO4

[ Molecular Weight ]:
183.161

[ Flash Point ]:
175.9±23.7 °C

[ Exact Mass ]:
183.053162

[ PSA ]:
75.28000

[ LogP ]:
0.55

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.574

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2909499000

Synthetic Route

Precursor & DownStream

Precursor

  • 3-Methoxy-4-nitrobenzoic acid
  • 3-Methoxy-4-nitrobenzaldehyde

DownStream

  • (4-Amino-3-methoxyphenyl)methanol
  • 4-(bromomethyl)-2-methoxy-1-nitrobenzene
  • 4-((benzyloxy)methyl)-2-methoxy-1-nitrobenzene
  • Dibenzyl ether
  • 4-(chloromethyl)-2-methoxy-1-nitrobenzene
  • 3-Methoxy-4-nitrobenzaldehyde

Customs

[ HS Code ]: 2909499000

[ Summary ]:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Can we predict reactivity for aromatic nucleophilic substitution with [18F] fluoride ion? Rengan R, et al.

J. Labelled Comp. Radiopharm. 33(7) , 563-572, (1993)

Trifluoromethyl-substituted hydantoins, versatile building blocks for rational drug design. Wehner V, et al.

Tetrahedron 60(19) , 4295-4302, (2004)

N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor.

J. Med. Chem. 46(14) , 3116-26, (2003)

Isosteric replacement of the phenolic hydroxyl group in potent vanilloid receptor (VR1) agonists with the alkylsulfonamido group provides a series of compounds which are effective antagonists to the a...


More Articles


Related Compounds

  • 4-(bromomethyl)-2-methoxy-1-nitrobenzene
  • 3-methoxy-4-benzoyloxybenzyl alcohol
  • 3-trifluoromethyl-4-nitrobenzyl alcohol
  • Methyl 4-(Hydroxymethyl)-2-Methoxybenzoate
  • 3-Methoxy-4-(Trifluoromethyl)Benzyl Alcohol
  • 3-Methoxy-4-(trifluoromethoxy)-benzyl alcohol
  • 6-Bromo-2-chloronicotinamide
  • 2-Bromo-4-chloro-3-(trifluoromethoxy)aniline
  • (3-fluoro-4-methylphenyl)((1R,5S)-3-methoxy-8-azabicyclo[3.2.1]octan-8-yl)methanone
  • 1-Chloro-4-(2,6-dichlorophenyl)butan-2-one
  • 2-[(1-{5H,6H,7H-pyrazolo[3,2-b][1,3]oxazine-3-carbonyl}pyrrolidin-3-yl)oxy]quinoxaline
  • N1-(4-iodo-2-pyridinyl)-1,2-benzenediamine
  • 3-(1-(1H-indole-2-carbonyl)piperidin-4-yl)thiazolidine-2,4-dione
  • 3-(1-(1H-indole-3-carbonyl)piperidin-4-yl)thiazolidine-2,4-dione
  • 6-fluoro-N-methyl-N-(1-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}azetidin-3-yl)quinazolin-4-amine
  • 3-(1-(2-(6-oxopyridazin-1(6H)-yl)acetyl)piperidin-4-yl)thiazolidine-2,4-dione
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