L-741,626

Suppliers

Names

[ Name ]:
L-741,626

[Synonym ]:
4-(4-Chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol
L 741,626
1-(indol-3-ylmethyl)-4-hydroxy-4-(p-chlorophenyl)piperidine
4-Piperidinol,4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)
3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole

Chemical & Physical Properties

[ Density]:
1.311g/cm3

[ Boiling Point ]:
548.8ºC at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₁ClN₂O

[ Molecular Weight ]:
340.84700

[ Flash Point ]:
285.7ºC

[ Exact Mass ]:
340.13400

[ PSA ]:
39.26000

[ LogP ]:
4.24280

[ Index of Refraction ]:
1.686

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Indole
4-(4-Chlorophenyl)-4-piperidinol
Gramine

DownStream

Articles

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma.

Oncotarget 5(4) , 882-93, (2014)

Glioblastoma remains one of the deadliest of human cancers, with most patients succumbing to the disease within two years of diagnosis. The available data suggest that simultaneous inactivation of cri...

3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor.

J. Med. Chem. 39 , 1941, (1996)

The role of the dopamine D2 receptor in descending control of pain induced by motor cortex stimulation in the neuropathic rat.

Brain Res. Bull. 89(3-4) , 133-43, (2012)

We studied in rats with a spinal nerve ligation-induced neuropathy whether dopamine D2 receptors (D2Rs) play a role in descending control of pain induced by stimulation of the primary motor cortex (M1...

L-741,742 hydrochloride,5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazolehydrochloride
5-[[3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidin-1-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one
L-741,742 hydrochloride
L-Malic acid dipotassium
L-Cysteine,S-(aminocarbonyl)-
L-Serine-13C3,15N
2-Amino-6-ethylphenol hydrochloride
1-(3-Amino-2-methylphenyl)ethan-1-ol
4-Amino-2-chloro-N-[2-(4-morpholinyl)ethyl]benzamide
N-[[4-(pyrrolidin-1-ylmethyl)phenyl]methyl]ethanamine
2,4-Dimethoxy-6-methylphenylmagnesium bromide
15,35,55,75-Tetrakis(2,4,4-trimethylpentan-2-yl)-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,32,52,72-tetraol
Tetracosanyl hexacosanoate
4-((2,5-dimethyl-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)morpholine oxalate
1-(2-Phenylpiperidin-1-yl)prop-2-en-1-one
N-(benzo[d]thiazol-2-yl)-N-(3-morpholinopropyl)-4-nitrobenzamide hydrochloride

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