2,4-Difluorophenylacetic acid

Suppliers

Names

[ Name ]:
2,4-Difluorophenylacetic acid

[Synonym ]:
MFCD00009999
(2,4-Difluorophenyl)acetic acid
QV1R BF DF
EINECS 279-709-4
2-(2,4-difluorophenyl)acetic acid
2,4-Difluorophenylacetic acid
Benzeneacetic acid, 2,4-difluoro-
2,4-Difluorobenzeneacetic acid
2,4-Difluorophenylaceticacid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
257.2±25.0 °C at 760 mmHg

[ Melting Point ]:
115-118 °C(lit.)

[ Molecular Formula ]:
C₈H₆F₂O₂

[ Molecular Weight ]:
172.129

[ Flash Point ]:
109.4±23.2 °C

[ Exact Mass ]:
172.033585

[ PSA ]:
37.30000

[ LogP ]:
1.65

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.508

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

(2,4-Difluorophenyl)acetyl chloride
α-bromo-(2,4-difluorophenyl)acetic acid
ALPHA-BROMO-4-FLUOROPHENYLACETIC ACID 9
Methyl 4-(2,4-difluorophenyl)-3-oxobutanoate
methyl 2-(2,4-difluorophenyl)acetate

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis of nonpolar peptide nucleic acid monomers containing fluoroaromatics. Shibata N, et al.

J. Chem. Soc. Perkin Trans. I 14 , 1605-11, (2001)

3-Ethoxy-2,4-difluorophenylacetic acid
3-chloro-2,4-difluorophenylacetic acid
2,4,5-Trifluorophenylacetic acid
2-BROMO-3,4-DIFLUOROPHENYLACETIC ACID
(4-Bromo-2,6-difluorophenyl)acetic acid
4-Ethoxy-2,3-Difluorophenylacetic Acid
2-(1-{6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl}cyclopropyl)ethan-1-amine
tert-butyl 4-[(3R)-3-aminobutyl]piperazine-1-carboxylate
2,2-difluoro-2-(1-methyl-1H-indol-4-yl)acetic acid
3-(3-Bromopyridin-2-yl)-1,1-difluoro-2-methylpropan-2-amine
[3-(1-ethyl-1H-pyrazol-3-yl)-2,2-dimethylcyclopropyl]methanamine
tert-butyl 6-(difluoromethyl)-2,3-dihydro-1H-indole-2-carboxylate
4,4-Difluoro-1-(6-methoxy-5-methylpyridin-3-yl)cyclohexan-1-amine
1-[1-(1-ethyl-1H-1,2,4-triazol-5-yl)cyclopropyl]ethan-1-one
4-[2-(1-Aminocyclopropyl)propan-2-yl]-2-bromophenol
3-(4-Fluoro-2-methylphenyl)-2-methoxypropanoic acid

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