2,4-Difluorophenylacetic acid

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Names

[ CAS No. ]:
81228-09-3

[ Name ]:
2,4-Difluorophenylacetic acid

[Synonym ]:
MFCD00009999
(2,4-Difluorophenyl)acetic acid
QV1R BF DF
EINECS 279-709-4
2-(2,4-difluorophenyl)acetic acid
2,4-Difluorophenylacetic acid
Benzeneacetic acid, 2,4-difluoro-
2,4-Difluorobenzeneacetic acid
2,4-Difluorophenylaceticacid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
257.2±25.0 °C at 760 mmHg

[ Melting Point ]:
115-118 °C(lit.)

[ Molecular Formula ]:
C8H6F2O2

[ Molecular Weight ]:
172.129

[ Flash Point ]:
109.4±23.2 °C

[ Exact Mass ]:
172.033585

[ PSA ]:
37.30000

[ LogP ]:
1.65

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.508

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Precursor & DownStream

Precursor

  • 2,4-Difluorobenzyl bromide

DownStream

  • (2,4-Difluorophenyl)acetyl chloride
  • α-bromo-(2,4-difluorophenyl)acetic acid
  • ALPHA-BROMO-4-FLUOROPHENYLACETIC ACID 9
  • Methyl 4-(2,4-difluorophenyl)-3-oxobutanoate
  • methyl 2-(2,4-difluorophenyl)acetate

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis of nonpolar peptide nucleic acid monomers containing fluoroaromatics. Shibata N, et al.

J. Chem. Soc. Perkin Trans. I 14 , 1605-11, (2001)


More Articles


Related Compounds

  • 3-Ethoxy-2,4-difluorophenylacetic acid
  • 3-chloro-2,4-difluorophenylacetic acid
  • 2,4,5-Trifluorophenylacetic acid
  • 2-BROMO-3,4-DIFLUOROPHENYLACETIC ACID
  • (4-Bromo-2,6-difluorophenyl)acetic acid
  • 4-Ethoxy-2,3-Difluorophenylacetic Acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • Tert-butyl 2-acetyl-2-(methoxymethyl)pyrrolidine-1-carboxylate
  • Methyl 4-bromo-2-cyano-3-(difluoromethyl)phenylacetate
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1-Bromo-5H-benzofuro[3,2-c]carbazole
  • [4-Methoxy-1-(2-trimethylsilylethoxymethyl)pyrazol-3-yl]methanol
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide