O-Desacetyl-N-desmethyl Diltiazem

Names

[ Name ]:
O-Desacetyl-N-desmethyl Diltiazem

[Synonym ]:
Deacetyl N-Monodesmethyl Diltiazem
3-Hydroxy-2-(4-methoxy-phenyl)-5-(2-methylamino-ethyl)-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one
3c-hydroxy-2r-(4-methoxy-phenyl)-5-(2-methylamino-ethyl)-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one
Diltiazem Impurity 7

Chemical & Physical Properties

[ Density]:
1.239g/cm3

[ Boiling Point ]:
612ºC at 760 mmHg

[ Melting Point ]:
134-136ºC (dec.)

[ Molecular Formula ]:
C₁₉H₂₂N₂O₃S

[ Molecular Weight ]:
358.45500

[ Flash Point ]:
323.9ºC

[ Exact Mass ]:
358.13500

[ PSA ]:
87.10000

[ LogP ]:
2.91140

[ Index of Refraction ]:
1.612

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(2S,3S)-3-HYDROXY-2-(4-METHOXY-PHEN YL)-2,3-DIHYDRO-5H-BENZO[B][1,4]THI AZEPIN-4-ONE
benzyl (2-chloroethyl)methylcarbamate

DownStream

Related Compounds

O-Desmethyl Diltiazem Hydrochloride
N-Desmethyl Diltiazem-d4 hydrochloride
N-Desmethyl Diltiazem Hydrochloride
o,n-di-desmethyl tramadol hcl
O-Desmethyl Pyrilamine
O,N-diacetyl-1,2-dimethyl-5-hydroxylaminoimidazole
6-chloro-1H-imidazo[4,5-b]pyridin-2-amine;hydrochloride
2-(aminomethyl)oxazole-4-carboxylic acid;2,2,2-trifluoroacetic acid
6-propylpyrazolo[1,5-a]pyrimidin-3-amine;hydrochloride
lithium;2-(5-methoxy-1,3,4-thiadiazol-2-yl)acetate
N-[2-amino-2-(2-methoxyphenyl)ethyl]-3,5,6-trimethyl-pyrazine-2-carboxamide;dihydrochloride
N-[(1-aminocycloheptyl)methyl]-1-cyclohexyl-pyrazole-3-carboxamide;dihydrochloride
N-[(1-benzylcyclohexyl)methyl]-1-isothiazol-4-yl-methanamine;hydrochloride
(2R,4R)-2-cyclopropylpiperidine-4-carboxamide;dihydrochloride
3-(4-aminophenoxy)benzaldehyde;hydrochloride
methyl 2-(aminomethyl)-1,1-dioxo-thiolane-2-carboxylate;hydrochloride