O-Desacetyl-N-desmethyl Diltiazem

Names

[ Name ]:
O-Desacetyl-N-desmethyl Diltiazem

[Synonym ]:
Deacetyl N-Monodesmethyl Diltiazem
3-Hydroxy-2-(4-methoxy-phenyl)-5-(2-methylamino-ethyl)-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one
3c-hydroxy-2r-(4-methoxy-phenyl)-5-(2-methylamino-ethyl)-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one
Diltiazem Impurity 7

Chemical & Physical Properties

[ Density]:
1.239g/cm3

[ Boiling Point ]:
612ºC at 760 mmHg

[ Melting Point ]:
134-136ºC (dec.)

[ Molecular Formula ]:
C₁₉H₂₂N₂O₃S

[ Molecular Weight ]:
358.45500

[ Flash Point ]:
323.9ºC

[ Exact Mass ]:
358.13500

[ PSA ]:
87.10000

[ LogP ]:
2.91140

[ Index of Refraction ]:
1.612

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(2S,3S)-3-HYDROXY-2-(4-METHOXY-PHEN YL)-2,3-DIHYDRO-5H-BENZO[B][1,4]THI AZEPIN-4-ONE
benzyl (2-chloroethyl)methylcarbamate

DownStream

Related Compounds

O-Desmethyl Diltiazem Hydrochloride
N-Desmethyl Diltiazem-d4 hydrochloride
N-Desmethyl Diltiazem Hydrochloride
o,n-di-desmethyl tramadol hcl
O-Desmethyl Pyrilamine
O,N-diacetyl-1,2-dimethyl-5-hydroxylaminoimidazole
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
cis-2-Methylpiperidin-3-OL hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
Ethyl 6-(2-oxa-6-azaspiro[3.3]heptan-6-yl)picolinate
N-(6-bromo-2,3-dimethylimidazo[1,2-a]pyridin-8-yl)-1-phenylmethanimine
2-[5-amino-3-(oxan-4-yl)-1H-pyrazol-1-yl]ethan-1-ol
N-cyclopropylpyrrolidine-1-sulfonamide
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
2-[Methyl[(tetrahydro-2H-pyran-4-yl)methyl]amino]propanenitrile