Alfuzosin hydrochloride

Suppliers

Names

[ CAS No. ]:
81403-68-1

[ Name ]:
Alfuzosin hydrochloride

[Synonym ]:
SL 77 499-10
N-{3-[(4-amino-6,7-diméthoxyquinazolin-2-yl)(méthyl)amino]propyl}tétrahydrofurane-2-carboxamide chlorhydrate
Uroxatral
MFCD00879135
N-{3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)(methyl)amino]propyl}tetrahydro-2-furancarboxamide hydrochloride (1:1)
2-furancarboxamide, N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-, monohydrochloride
Alfuzosin HCl
N-{3-[(4-Amino-6,7-dimethoxychinazolin-2-yl)(methyl)amino]propyl}tetrahydrofuran-2-carboxamidhydrochlorid
2-Furancarboxamide, N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-, hydrochloride (1:1)
SL 77-499-10
Alfuzosin hydrochloride
N-{3-[(4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}tetrahydrofuran-2-carboxamide hydrochloride (1:1)
Alfuzosin (hydrochloride)

Chemical & Physical Properties

[ Density]:
1.272 g/cm3

[ Boiling Point ]:
687.7ºC at 760 mmHg

[ Melting Point ]:
225°C

[ Molecular Formula ]:
C19H28ClN5O4

[ Molecular Weight ]:
425.910

[ Exact Mass ]:
425.182983

[ PSA ]:
111.83000

[ LogP ]:
3.12480

[ Storage condition ]:
Store at RT

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Precautionary Statements ]:
P301 + P312 + P330

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Alfuzosin
  • N1-methyl-N1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1,3-propanediamine
  • 1-(tetrahydrofuran-2-ylcarbonyl)-1H-imidazole
  • Tetrahydro-2-furancarbonyl chloride
  • 2-Tetrahydrofuroic acid
  • PHYTASE
  • N-[3-(methylamino)propyl]oxolane-2-carboxamide
  • 2-Chloro-6,7-dimethoxyquinazolin-4-amine
  • (R,S)-N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide acetate

DownStream

  • Alfuzosin

Articles

Comparison ofcore–shelland totally porous ultra high performance liquid chromatographic stationary phases based on their selectivity towards alfuzosin compounds

J. Chromatogr. A. 1346 , 69-77, (2014)

• KUL procedure was adapted to testing of UHPLC stationary phases. • Classification of core–shell and UHPLC columns was performed. • Verification of the KUL results was based on the separation of alfu...

Temperature influencing permeation pattern of alfuzosin: an investigation using DoE.

Medicina (Kaunas.) 51 , 253-61, (2015)

There has been relatively little investigation of the effect of temperature on skin permeation compared to other methods of penetration enhancement. A principal physicochemical factor which controls t...


More Articles

Related Compounds

  • N2-Methyl Alfuzosin Hydrochloride
  • Alfuzosin hydrochloride impurity A
  • 2,3,4,5-tetradehydro alfuzosin hydrochloride
  • 2,3,4,5-Tetradehydro Alfuzosin Hydrochloride
  • Alfuzosin-d3 hydrochloride
  • Alfuzosin-d3
  • N-(3-hydroxy-4,4-dimethylpentyl)cyclopropanecarboxamide
  • 3,5-Dimethyl-1-(prop-2-en-1-yl)cyclohexan-1-ol
  • 4-(Aminomethyl)chroman-4-carboxylic acid
  • 3-Cyclobutyl-7-methyl-3H-imidazo[4,5-b]pyridin-2-amine
  • 4-Tert-butyl-1-cyanocyclohexane-1-carboxylic acid
  • 1-Cyano-4-(propan-2-yl)cyclohexane-1-carboxylic acid
  • 3-(1-(Aminomethyl)cyclobutyl)-2-methylpentan-3-ol
  • [1-(Aminomethyl)cyclopentyl](cyclopropyl)methanol
  • 1-Amino-2,2,5,5-tetramethylhexan-3-ol
  • Methyl 3-[(4-bromo-2-fluorophenyl)amino]-2,2-dimethylpropanoate
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