(E)-7-[2-morpholin-4-yl-3-oxo-5-[(4-phenylphenyl)methoxy]cyclopentyl]hept-4-enoic acid

Names

[ CAS No. ]:
81443-73-4

[ Name ]:
(E)-7-[2-morpholin-4-yl-3-oxo-5-[(4-phenylphenyl)methoxy]cyclopentyl]hept-4-enoic acid

Chemical & Physical Properties

[ Density]:
1.21g/cm3

[ Boiling Point ]:
657.5ºC at 760 mmHg

[ Molecular Formula ]:
C29H35NO5

[ Molecular Weight ]:
477.59200

[ Flash Point ]:
351.4ºC

[ Exact Mass ]:
477.25200

[ PSA ]:
76.07000

[ LogP ]:
4.66770

[ Index of Refraction ]:
1.603

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MJ9651150
CHEMICAL NAME :
4-Heptenoic acid, 7-(5-((1,1'-biphenyl)-4-ylmethoxy)-2-(4-morpholinyl)- 3-oxocyclopentyl)-, (1-alpha(Z),2-beta,5-alpha)-(+-)-
CAS REGISTRY NUMBER :
81443-73-4
LAST UPDATED :
199706
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C29-H35-N-O5
MOLECULAR WEIGHT :
477.65

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
750 mg/kg
SEX/DURATION :
female 12-16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - body wall
REFERENCE :
ParMM# Personal Communication from M.M. Parkinson, Glaxo Group Research Limited, Ware, Hertfordshire, SG12 0DJ, UK, Mar. 24, 1987 Volume(issue)/page/year: 24MAR1987
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1500 mg/kg
SEX/DURATION :
female 12-16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 39,537,1989

Related Compounds

  • 6-(3,5-dimethylpiperidin-1-yl)-9-ethyl-9H-purine
  • 1-(3-Bromophenyl)-4-[(pyridin-4-yl)methyl]piperazine
  • 5-{2-[Methyl(propan-2-yl)amino]ethyl}-1,2-oxazol-4-amine
  • 9-amino-N-propyl-1-oxa-4-azaspiro[5.5]undecane-4-carboxamide
  • (2S)-4-(4-fluoro-3-nitrophenyl)butan-2-amine
  • 1-(1-Bromopropan-2-yl)-2-chloro-3-fluorobenzene
  • 1-(4-Bromophenyl)-4-[(pyridin-3-yl)methyl]piperazine
  • 9-amino-N-(2-methylpropyl)-1-oxa-4-azaspiro[5.5]undecane-4-carboxamide
  • 2,2-Difluoro-2-(3-methoxy-1,2-oxazol-5-yl)ethan-1-amine
  • 1-(4-Bromophenyl)-4-[(pyridin-2-yl)methyl]piperazine
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