1,2-Distearoyl-sn-glycero-3-phosphocholine

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Names

[ CAS No. ]:
816-94-4

[ Name ]:
1,2-Distearoyl-sn-glycero-3-phosphocholine

[Synonym ]:
EINECS 212-440-2
MFCD00036905
(2R)-2,3-Bis(stearoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
1,2-Distearoyl-sn-glycero-3-phosphocholine
Ethanaminium, 2-[[[(2R)-2,3-bis[(1-oxooctadecyl)oxy]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
(2R)-2,3-bis(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
L-α-PHOSPHATIDYLCHOLINE, DISTEAROYL

Chemical & Physical Properties

[ Melting Point ]:
236 °C

[ Molecular Formula ]:
C44H88NO8P

[ Molecular Weight ]:
790.145

[ Exact Mass ]:
789.624756

[ PSA ]:
121.00000

[ LogP ]:
13.00

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Octadecanoic acid,ethenyl ester
  • L-α-glycerophosphorylcholine
  • 1,2-distearoyl-rac-glycerol
  • 1,2-linoleoylphosphatidylcholine
  • α-[α'-Linoleoyl-β-stearoyl]-phosphatidylcholin
  • 1,2-Dilinoleoyl-sn-glycerol
  • 2-(1,2-Distearoyl-rac-3-glyceryl)-1,3,2-dioxaphospholan
  • β-Stearoyl-α-linoleoyl-glycerin
  • Choline chloride
  • α-[α'-Linoleoyl-β-stearoyl]-phosphadidyl-ethylenbromhydrin

DownStream

  • Choline chloride
  • 1-Stearoyl-sn-glycero-3-phosphocholine

Articles

Immunoliposomes containing Soluble Leishmania Antigens (SLA) as a novel antigen delivery system in murine model of leishmaniasis.

Exp. Parasitol. 146 , 78-86, (2014)

Development of new generation of vaccines against leishmaniasis requires adjuvants to elicit the type and intensity of immune response needed for protection. The coupling of target-specific antibodies...

Defective functionality of HDL particles in familial apoA-I deficiency: relevance of alterations in HDL lipidome and proteome.

J. Lipid Res. 55(12) , 2509-20, (2014)

To evaluate functional and compositional properties of HDL in subjects from a kindred of genetic apoA-I deficiency, two homozygotes and six heterozygotes, with a nonsense mutation at APOA1 codon -2, Q...

Ultrasound triggered drug delivery with liposomal nested microbubbles.

Ultrasonics 63 , 31-8, (2015)

When ultrasound contrast agent microbubbles are nested within a liposome, damage to the liposome membrane caused by both stable and inertial cavitation of the microbubble allows for release of the aqu...


More Articles

Related Compounds

  • 1,2-distearoyl-sn-glycero-3-phosphocholine
  • 1,2-distearoyl-sn-glycero-3-phosphocholine
  • 1,2-Distearoyl-sn-glycero-3-phosphocholine
  • 1,2-distearoyl-sn-glycero-3-phosphocholine
  • 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE DIHYDRATE
  • 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d79
  • 5-(3-Chloro-5-fluorophenyl)-1,2-oxazol-4-amine
  • tert-butyl N-[2-hydroxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate
  • 4,4-Dimethyl-3-methylidenehexan-1-amine
  • tert-butyl N-[3-cyano-1-(4-hydroxyphenyl)-4,5-dimethyl-1H-pyrrol-2-yl]carbamate
  • tert-butyl N-[2-(4-hydroxy-5-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)ethyl]carbamate
  • Methyl 3-(azetidin-3-yl)thiophene-2-carboxylate
  • rac-(3R,4S)-1-[(tert-butoxy)carbonyl]-4-(2-methoxy-5-methylphenyl)pyrrolidine-3-carboxylic acid
  • 1-[3-(aminomethyl)but-3-en-1-yl]-1H-1,2,4-triazole
  • tert-butyl 2-[(1R)-1-amino-2-hydroxyethyl]morpholine-4-carboxylate
  • tert-butyl N-(3-hydroxyphenyl)-N-(5-methyl-1,3-thiazol-2-yl)carbamate
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