Vintriptol
Suppliers
Names
[ CAS No. ]:
81600-06-8
[ Name ]:
Vintriptol
[Synonym ]:
Vintriptyl acetate
UNII-8RV67I06A5
Vinblastine tryptophan ester
ethyl N-(O-4-deacetyl-vinblastin-23-oyl)-L-tryptophanate
Vincaleukoblastine,3-de(methoxycarbonyl)-3-((((1S)-2-ethoxy-1-(1H-indol-3-ylmethyl)-2-oxoethyl)amino)carbonyl)
Chemical & Physical Properties
[ Density]:
1.4g/cm3
[ Molecular Formula ]:
C56H68N6O9
[ Molecular Weight ]:
969.17400
[ Exact Mass ]:
968.50500
[ PSA ]:
192.92000
[ LogP ]:
5.35070
[ Index of Refraction ]:
1.708
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YY8158000
- CHEMICAL NAME :
- Vincaleukoblastine, O(sup 4)-deacetyl-3-de(methoxycarbonyl)-3-(((2-ethoxy-1-(1H -indol-3- ylmethyl)-2-oxoethyl)amino)carbonyl)-, (23(S))-
- CAS REGISTRY NUMBER :
- 81600-06-8
- LAST UPDATED :
- 199403
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C56-H68-N6-O9
- MOLECULAR WEIGHT :
- 969.30
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 94 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 28,1079,1985