Acetamide,N-(2-amino-2-oxoethyl)-2-diazo-

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Names

[ CAS No. ]:
817-99-2

[ Name ]:
Acetamide,N-(2-amino-2-oxoethyl)-2-diazo-

[Synonym ]:
Diazoacetyl-aminoessigsaeureamid
N-(2-diazoacetyl)glycinamide
ACETAMIDE,N-(CARBAMOYLMETHYL)-2-DIAZO
N-Diazoacetyl-glycin-amid
N-diazoacetyl-glycine amide
Diazoacetoglycinamid
N-(Carbamoylmethyl)-2-diazoacetamide
N-(DIAZOACETYL)-GLYCINAMIDE
N-(2-Amino-2-oxoethyl)-2-diazoacetamide

Chemical & Physical Properties

[ Molecular Formula ]:
C4H6N4O2

[ Molecular Weight ]:
142.11600

[ Exact Mass ]:
142.04900

[ PSA ]:
109.58000

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB4900000
CHEMICAL NAME :
Acetamide, N-(carbamoylmethyl)-2-diazo-
CAS REGISTRY NUMBER :
817-99-2
LAST UPDATED :
199410
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C4-H6-N4-O2
MOLECULAR WEIGHT :
142.14
WISWESSER LINE NOTATION :
ZV1MV1UNN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2630 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
720 mg/kg/4D-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - leukemia
TYPE OF TEST :
DNA damage
TYPE OF TEST :
DNA damage

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
150 umol/L
REFERENCE :
BSIBAC Bolletino della Societe Italiana di Biologia Sperimentale. (Casa Editrice Idelson, Via A. de Gasperi, 55, 80133 Naples, Italy) V.2- 1927- Volume(issue)/page/year: 57,1282,1981

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Glycine,N-(diazoacetyl)-, ethyl ester (7CI,8CI,9CI)
  • Ammonia
  • Water

DownStream

Related Compounds

  • 4H-1,4-Benzoxazine-4-acetamide,N-(2-amino-2-oxoethyl)-2,3-dihydro-2-methyl-3-oxo-(9CI)
  • 2-(N-(2-chloroacetyl)-2,6-diethylanilino)acetamide
  • Acetamide, N-[2-[(4-bromophenyl)amino]-2-oxoethyl]-2-chloro
  • Benzamide, N-(2-amino-2-oxoethyl)-2-(3,3-dimethyl-1-triazenyl)-
  • (2S)-N-(2-amino-2-oxoethyl)-2-[[(2S)-2-aminopropanoyl]amino]-4-methylpentanamide
  • (E)-N-(2-amino-2-oxoethyl)-2-propylpent-2-enamide
  • 9H-Fluoren-9-amine, 2,7-dichloro-
  • 1-(2-Methoxy-6-methylphenyl)cyclopropanecarboxylic acid
  • 4-Phenyloxane-3-carboxylic acid
  • 2-(3-Amino-1-ethylpyrrolidin-3-yl)acetic acid
  • 6-(Difluoromethyl)-1,3-dioxaindane-5-carboxylic acid
  • 2-Pentanone, 2,2a(2),2a(2)a(2)-[O,Oa(2),Oa(2)a(2)-(phenylsilylidyne)trioxime]
  • (4S)-2,2-dimethyl-4-(prop-2-yn-1-yl)-1,3-dioxolane
  • 2-{[(Tert-butoxy)carbonyl]amino}-4-hydroxy-5,5-dimethylhexanoic acid
  • 5-(3,3-Dimethyl-2-oxiranyl)-1-ethyl-1H-pyrazole-3-carbonitrile
  • 3 inverted exclamation mark-Fluoro-5 inverted exclamation mark-(methylsulphonyl)acetophenone
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