Rubomycin M

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Names

[ Name ]:
Rubomycin M

[Synonym ]:
7-O-(Triethylsilyl) Paclitaxel
(|AR,|AS)-|A-(Benzoylamino)-|A-hydroxy-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester
7-triethylsilyl taxol

Chemical & Physical Properties

[ Density]:
1.53g/cm3

[ Boiling Point ]:
863.3ºC at 760mmHg

[ Molecular Formula ]:
C₃₃H₃₉NO₁₃

[ Molecular Weight ]:
657.66200

[ Flash Point ]:
475.9ºC

[ Exact Mass ]:
657.24200

[ PSA ]:
224.53000

[ LogP ]:
1.61020

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

7-O-[4-O-(3,4-di-O-acetyl-2,6-didesoxy-α-L-lyxo-hexopyranosyl)-2,3,6-tridesoxy-3-(trifluoroacetamido)-α-L-lyxo-hexopyranosyl]daunomycinone
7-O-[4-O-(2,6-didesoxy-α-L-lyxo-hexopyranosyl)-2,3,6-tridesoxy-3-(trifluoroacetamido)-α-L-lyxo-hexopyranosyl]daunomycinone
benzyl 2,3,6-trideoxy-3-trifluoroacetamido-α-L-lyxo-hexopyranoside
benzyl 4-O-acetyl-N-(trifluoroacetyl)-L-daunosamide
benzyl 2,3,6-trideoxy-4-O-(3,4-di-O-acetyl-2,6-dideoxy-α-L-lyxo-hexopyranosyl)-3-trifluoroacetamido-α-L-lyxo-hexopyranoside
4-O-acetyl-N-(trifluoroacetyl)-L-daunosaminyl bromide
1,3,4-Tri-O-acetyl-2-deoxy-α/β-L-fucopyranose