Bambuterol Hydrochloride

Suppliers

Names

[ Name ]:
Bambuterol Hydrochloride

[Synonym ]:
(±)-Bambuterol hydrochloride
[3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate,hydrochloride
Bambuterol hydrochloride
5-[2-(tert-Butylamino)-1-hydroxyethyl]-1,3-phenylene bis(dimethylcarbamate) hydrochloride (1:1)
5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diyl bis(dimethylcarbamate) hydrochloride (1:1)
Carbamic acid, N,N-dimethyl-, 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester, hydrochloride (1:1)
5-{1-Hydroxy-2-[(2-methyl-2-propanyl)amino]ethyl}-1,3-phenylene bis(dimethylcarbamate) hydrochloride (1:1)
UNII:786Q84QZ3F
MFCD03427293
Bambec
Bambuterol (hydrochloride)

Chemical & Physical Properties

[ Density]:
1.154g/cm3

[ Boiling Point ]:
500.9ºC at 760 mmHg

[ Melting Point ]:
222-224ºC

[ Molecular Formula ]:
C₁₈H₃₀ClN₃O₅

[ Molecular Weight ]:
403.901

[ Flash Point ]:
256.7ºC

[ Exact Mass ]:
403.187408

[ PSA ]:
91.34000

[ LogP ]:
3.42180

[ Index of Refraction ]:
1.533

[ Storage condition ]:
-20°C Freezer

[ Water Solubility ]:
H2O: ~33 mg/mL, soluble

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Chiral analysis of bambuterol, its intermediate and active drug in human plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 997 , 38-44, (2015)

A sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed for simultaneous chiral analysis of an antiasthma drug bambuterol, its key intermediate monocarbamate ba...

Simultaneous determination of bambuterol and its two major metabolites in human plasma by hydrophilic interaction ultra-performance liquid chromatography-tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 225-34, (2014)

In this study, a rapid and sensitive hydrophilic interaction ultra-performance liquid chromatography-tandem mass spectrometry (HILIC-UPLC-MS/MS) method was developed for simultaneous determination of ...

Pharmacokinetics of bambuterol during oral administration of plain tablets and solution to healthy adults.

Br. J. Clin. Pharmacol. 49 , 199-206, (2000)

The pharmacokinetics of orally administered bambuterol were investigated in healthy adult subjects, with particular regard to time to steady state, pharmacokinetic linearity, intraindividual variabili...

(R)-bambuterol hydrochloride
benzyl N-[(2S)-4-amino-1-[[(2S,3R)-4-[(2S)-2-(tert-butylcarbamoyl)piperidin-1-yl]-3-hydroxy-1-phenylbutan-2-yl]amino]-1,4-dioxobutan-2-yl]carbamate
[3-[2-(tert-butylamino)-1-hydroxyethyl]-5-hydroxyphenyl] N,N-dimethylcarbamate,hydrochloride
carnitine hydrochloride
Losoxantrone hydrochloride [USAN]
Triprolidine hydrochloride
Ethyl 2-(5-chloro-2-nitrophenoxy)acetate
2-(methylsulfanyl)-N-({4'-[(2-oxopyrrolidin-1-yl)methyl]-[1,1'-biphenyl]-2-yl}methyl)pyridine-3-carboxamide
4-Methylpentane-1-sulfonamide
2,4-dimethoxy-N-(2-(4-methylpiperazin-1-yl)-2-(thiophen-3-yl)ethyl)benzenesulfonamide
4-isopropyl-N-(2-(4-methylpiperazin-1-yl)-2-(thiophen-3-yl)ethyl)benzenesulfonamide
4-methoxy-3,5-dimethyl-N-(2-(4-methylpiperazin-1-yl)-2-(thiophen-3-yl)ethyl)benzenesulfonamide
4-methoxy-2-methyl-N-(2-(4-methylpiperazin-1-yl)-2-(thiophen-3-yl)ethyl)benzenesulfonamide
4-ethoxy-3-fluoro-N-(2-(4-methylpiperazin-1-yl)-2-(thiophen-3-yl)ethyl)benzenesulfonamide
N-(2-(4-methylpiperazin-1-yl)-2-(thiophen-3-yl)ethyl)-1-phenylmethanesulfonamide
2,4,6,8-Nonatetraenal, 9-(4-methoxyphenyl)-3,7-dimethyl-, (all-E)-

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