cafestol acetate

Suppliers

Names

[ CAS No. ]:
81760-48-7

[ Name ]:
cafestol acetate

[Synonym ]:
MFCD00133152
O-Acetyl-cafestol

Chemical & Physical Properties

[ Density]:
1.21g/cm3

[ Boiling Point ]:
474.6ºC at 760mmHg

[ Molecular Formula ]:
C22H30O4

[ Molecular Weight ]:
358.47100

[ Flash Point ]:
240.8ºC

[ Exact Mass ]:
358.21400

[ PSA ]:
59.67000

[ LogP ]:
4.21010

[ Index of Refraction ]:
1.578

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Cafestol
  • Ethanoic anhydride

DownStream

Articles

Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver.

Food Chem. Toxicol. 46 , 1230-1238, (2008)

Coffee drinking appears to reduce cancer risk in liver and colon. Such chemoprevention may be caused by the diterpenes kahweol and cafestol (K/C) contained in unfiltered beverage. In animals, K/C trea...

Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage.

Toxicol. Lett. 173 , 80-87, (2007)

There is an increasing evidence that oxidative stress is implicated in the processes of inflammation and carcinogenesis. It has been shown that kahweol and cafestol, coffee-specific diterpenes, exhibi...

Inhibition of the fungal fatty acid synthase type I multienzyme complex.

Proc. Natl. Acad. Sci. U. S. A. 105 , 12803-8, (2008)

Fatty acids are among the major building blocks of living cells, making lipid biosynthesis a potent target for compounds with antibiotic or antineoplastic properties. We present the crystal structure ...


More Articles

Related Compounds

  • Cafestol palmitate
  • Cafestol
  • Menthyl acetate
  • Glutinol acetate
  • Germanicol acetate
  • Cupric acetate monohydrate
  • N-[5-(4-{2-methylpyrazolo[1,5-a]pyrazin-4-yl}piperazin-1-yl)pyridin-2-yl]cyclopropanecarboxamide
  • 2-{4-[4-(pyridin-3-yl)pyrimidin-2-yl]piperazin-1-yl}-5H,7H,8H-pyrano[4,3-b]pyridine-3-carbonitrile
  • 6-Cyclopropyl-2-(4-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperazin-1-yl)-3,4-dihydropyrimidin-4-one
  • 6-cyclopropyl-2-(4-{1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}piperazin-1-yl)-3,4-dihydropyrimidin-4-one
  • 1-(6-methoxypyridin-2-yl)-4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperazine
  • N-(2-ethoxyphenyl)-2-[3-(trifluoromethyl)azetidin-1-yl]acetamide
  • 2,2-dimethyl-N-(5-{4-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperazin-1-yl}pyridin-2-yl)propanamide
  • 2-[3-(Pyridin-2-yl)pyrrolidin-1-yl]-1,3-benzoxazole
  • N-{5-[4-(9-methyl-9H-purin-6-yl)piperazin-1-yl]pyridin-2-yl}cyclopropanecarboxamide
  • N-{5-[4-(7-methyl-7H-purin-6-yl)piperazin-1-yl]pyridin-2-yl}cyclopropanecarboxamide
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