Acenaphthoquinone

Names

[ CAS No. ]:
82-86-0

[ Name ]:
Acenaphthoquinone

[Synonym ]:
acenaphthenequinone
MFCD00003805
Acenaphthoquinone
EINECS 201-441-3
1,2-Acenaphthylenedione
acenaphthylene-1,2-dione

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
362.5±9.0 °C at 760 mmHg

[ Melting Point ]:
249-252 °C (dec.)(lit.)

[ Molecular Formula ]:
C₁₂H₆O₂

[ Molecular Weight ]:
182.175

[ Flash Point ]:
150.2±4.4 °C

[ Exact Mass ]:
182.036774

[ PSA ]:
34.14000

[ LogP ]:
2.28

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.746

[ Water Solubility ]:
INSOLUBLE

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AB1024500

CHEMICAL NAME :: Acenaphthenedione

CAS REGISTRY NUMBER :: 82-86-0

BEILSTEIN REFERENCE NO. :: 0879172

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H6-O2

MOLECULAR WEIGHT :: 182.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 728 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 41,146,1978

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
UN 2920

[ WGK Germany ]:
3

[ RTECS ]:
AB1024500

[ Packaging Group ]:
II; III

[ Hazard Class ]:
4.1

[ HS Code ]:
29146990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Acenaphthene
Acenaphthylene
Acenaphthylene,1,2-dibromo-1,2-dihydro-
1,2-Didehydroacenaphthylene
Ethyl 2-oxo-3'-phenylspiro[acenaphthylene-1-(2H),5'(4'H)-isoxazole]-4'-carboxylate
1,2-Acenaphthylenediol,1,2-dihydro-, (1R,2S)-rel-
(±)-trans-acenaphthene-1,2-diol
Acenaphthenone
1H-Phenalene-1,2,3-trione
2,2-dihydroxyphenalene-1,3-dione

DownStream

Propanedinitrile,2-(2-oxo-1(2H)-acenaphthylenylidene)-
1,2-Acenaphthylenediol, 1,2-dihydro-
Phosphine oxide, 1,1'-(1,2-ethanediyl)bis[diphenyl-
3-aminophenalen-1-one
8-methylfluoranthene
Methanone,1,1'-(1,8-naphthalenediyl)bis[1-phenyl-
2-[2,6-di(propan-2-yl)phenyl]iminoacenaphthylen-1-one
(2Z)-2-hydrazinylideneacenaphthen-1-one
N-[[2-(phenylhydrazinylidene)acenaphthen-1-ylidene]amino]aniline

Customs

[ HS Code ]: 2914399090

[ Summary ]:
2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Addition of phenylacetylene to a magnesium complex of monoiminoacenaphtheneone (dpp-mian).

Dalton Trans. 44 , 20532-41, (2015)

In the presence of formic acid, acenaphthenequinone (AQ) reacts with one molar equivalent of 2,6-diisopropylaniline in toluene to give monoiminoacenaphtheneone (3, dpp-mian) in good yield. Reduction o...

Planarity and constraint of the carbonyl groups in 1,2-diones are determinants for selective inhibition of human carboxylesterase 1.

J. Med. Chem. 50 , 5727-34, (2007)

Carboxylesterases (CE) are ubiquitous enzymes responsible for the detoxification of xenobiotics, including numerous clinically used drugs. Therefore, the selective inhibition of these proteins may pro...

CaCl(2) as a bifunctional reusable catalyst: diversity-oriented synthesis of 4H-pyran library under ultrasonic irradiation.

Mol. Divers. 16(4) , 669-83, (2012)

CaCl(2) is applied as an efficient reusable and eco-friendly bifunctional catalyst for the one-pot three-component synthesis of 4H-pyrans under ultrasonic irradiation. A broad range of substrates incl...