dl-methionine sulfone

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Names

[ CAS No. ]:
820-10-0

[ Name ]:
dl-methionine sulfone

[Synonym ]:
methionine S,S-dioxide
DL-LOBAMINE SULFONE
METHIONINESULPHONE
DL-METHIONINE SULFONE
DL-BANTHIONINE SULFONE
EINECS 212-466-4
Butanoic acid, 2-amino-4-(methylsulfonyl)-
methionine sulfoxide
2-Amino-4-(methylsulfonyl)butanoic acid
Methionine sulfone
MFCD00025079
DL-methionine S-dioxide
UNII:5503K54L0R

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
450.5±40.0 °C at 760 mmHg

[ Melting Point ]:
250ºC

[ Molecular Formula ]:
C5H11NO4S

[ Molecular Weight ]:
181.210

[ Flash Point ]:
226.3±27.3 °C

[ Exact Mass ]:
181.040878

[ PSA ]:
105.84000

[ LogP ]:
-1.27

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.512

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • DL-Methionine
  • H-Met(O)-OH
  • acetylamino-(2-methanesulfonyl-ethyl)-malonic acid diethyl ester
  • Hydrogen peroxide

DownStream

  • (2S)-2-Amino-4-(Methylsulfonyl)-Butanoic Acid
  • HD-Met(O2)-OH

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

In Salmonella enterica, the Gcn5-related acetyltransferase MddA (formerly YncA) acetylates methionine sulfoximine and methionine sulfone, blocking their toxic effects.

J. Bacteriol. 197(2) , 314-25, (2015)

Protein and small-molecule acylation reactions are widespread in nature. Many of the enzymes catalyzing acylation reactions belong to the Gcn5-related N-acetyltransferase (GNAT; PF00583) family, named...

Copper(II) complexes of neurokinin A with point mutation (S5A) and products of copper-catalyzed oxidation; role of serine residue in peptides containing neurokinin A sequence.

J. Inorg. Biochem. 121 , 1-9, (2013)

A potentiometric, spectroscopic (UV-visible, CD and EPR) and electrospray ionization mass spectrometric (ESI-MS) study of Cu(II) binding to the neurokinin A with point mutation (S5A) (ANKA), His-Lys-T...

Analysis of methionine oxides and nitrogen-transporting amino acids in chilled and acclimated maize seedlings.

Amino Acids 33(4) , 607-13, (2007)

In maize seedlings, chilling causes a reduction of glutamine synthetase (GS) activity, while acclimation protects GS (manuscript submitted). Since ROS can oxidize both protein-bound and free Met to me...


More Articles

Related Compounds

  • DNP-DL-methionine sulfone
  • DL-methionine , copper (II)-salt
  • DL-Methionine, N- (2-cyanoethyl)-
  • dl-methionine-2-d1
  • DL-METHIONINE SULFOXIDE
  • DL-Methionine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • tert-butyl N-[5-methoxy-2-(3,3,3-trifluoro-2-oxopropyl)phenyl]carbamate
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide