dl-methionine sulfone

Suppliers

Names

[ CAS No. ]:
820-10-0

[ Name ]:
dl-methionine sulfone

[Synonym ]:
methionine S,S-dioxide
DL-LOBAMINE SULFONE
METHIONINESULPHONE
DL-METHIONINE SULFONE
DL-BANTHIONINE SULFONE
EINECS 212-466-4
Butanoic acid, 2-amino-4-(methylsulfonyl)-
methionine sulfoxide
2-Amino-4-(methylsulfonyl)butanoic acid
Methionine sulfone
MFCD00025079
DL-methionine S-dioxide
UNII:5503K54L0R

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
450.5±40.0 °C at 760 mmHg

[ Melting Point ]:
250ºC

[ Molecular Formula ]:
C₅H₁₁NO₄S

[ Molecular Weight ]:
181.210

[ Flash Point ]:
226.3±27.3 °C

[ Exact Mass ]:
181.040878

[ PSA ]:
105.84000

[ LogP ]:
-1.27

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.512

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

In Salmonella enterica, the Gcn5-related acetyltransferase MddA (formerly YncA) acetylates methionine sulfoximine and methionine sulfone, blocking their toxic effects.

J. Bacteriol. 197(2) , 314-25, (2015)

Protein and small-molecule acylation reactions are widespread in nature. Many of the enzymes catalyzing acylation reactions belong to the Gcn5-related N-acetyltransferase (GNAT; PF00583) family, named...

Copper(II) complexes of neurokinin A with point mutation (S5A) and products of copper-catalyzed oxidation; role of serine residue in peptides containing neurokinin A sequence.

J. Inorg. Biochem. 121 , 1-9, (2013)

A potentiometric, spectroscopic (UV-visible, CD and EPR) and electrospray ionization mass spectrometric (ESI-MS) study of Cu(II) binding to the neurokinin A with point mutation (S5A) (ANKA), His-Lys-T...

Analysis of methionine oxides and nitrogen-transporting amino acids in chilled and acclimated maize seedlings.

Amino Acids 33(4) , 607-13, (2007)

In maize seedlings, chilling causes a reduction of glutamine synthetase (GS) activity, while acclimation protects GS (manuscript submitted). Since ROS can oxidize both protein-bound and free Met to me...