diethyldiazene

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Names

[ CAS No. ]:
821-14-7

[ Name ]:
diethyldiazene

[Synonym ]:
Azobisethane
ETHANE,AZO
Diaethyl-diazen
AZOETHANE

Chemical & Physical Properties

[ Molecular Formula ]:
C₄H₁₀N₂

[ Molecular Weight ]:
86.13560

[ Exact Mass ]:
86.08440

[ PSA ]:
24.72000

[ LogP ]:
1.47840

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KH4025000

CHEMICAL NAME :: Ethane, azo-

CAS REGISTRY NUMBER :: 821-14-7

BEILSTEIN REFERENCE NO. :: 1736139

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C4-H10-N2

MOLECULAR WEIGHT :: 86.16

WISWESSER LINE NOTATION :: 2NUN2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 67,31,1965 ** TUMORIGENIC DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 37 mg/kg/1H female 22 day(s) after conception

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Brain and Coverings - tumors

REFERENCE :: IARCCD IARC Scientific Publications. (Geneva, Switzerland) No.1-26, 1971-78. For publisher information, see IAPUDO. Volume(issue)/page/year: 4,45,1973

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1250 mg/kg/26W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Blood - leukemia

REFERENCE :: ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 67,31,1965

TYPE OF TEST :: TC - Toxic concentration (other than lowest)

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4000 ppm/1H female 15 day(s) after conception

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Brain and Coverings - tumors

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 6,584,1968

TYPE OF TEST :: TC - Toxic concentration (other than lowest)

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 mg/kg/1H female 15 day(s) after conception

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Brain and Coverings - tumors

REFERENCE :: EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 24,561,1968 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 1250 mg/kg/1H

SEX/DURATION :: female 15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :: IARCCD IARC Scientific Publications. (Geneva, Switzerland) No.1-26, 1971-78. For publisher information, see IAPUDO. Volume(issue)/page/year: 4,45,1973

Related Compounds

diethyldiazene
diethyldiazene (Z)-N-oxide
diethyldiazene (Z)-N-oxide
(E)-diethyldiazene N,N'-dioxide
2,5-Dioxopyrrolidin-1-yl 4-((cyclooct-4-en-1-yloxy)methyl)benzoate
(3-Fluorophenyl)(2,7-diazaspiro[4.4]nonan-2-yl)methanone
2-Propargyl-1-methyl-piperidine
4-Mercapto-3,5-dimethoxybenzaldehyde
1-Amino-4-propylheptan-3-ol
1-(3-Aminoazetidin-1-yl)-2-propylpentan-1-one
2-Chloro-3,5-dihydroxybenzaldehyde
Ethanone, 1-(3-bromo-4-methylphenyl)-2-(2-nitrophenyl)-
[(3-Bromo-4-methylphenyl)methyl](2-methylpropyl)amine
4-(Aminomethyl)-7-fluoro-1,2,3,4-tetrahydroquinolin-2-one

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