2,6-diaminotoluene
Suppliers
Names
[ CAS No. ]:
823-40-5
[ Name ]:
2,6-diaminotoluene
[Synonym ]:
2-Methyl-m-phenylenediamine
2-Methyl-1,3-benzenediamine
2,6-toluenediamine
MFCD00007800
2,6-diaminotoluene
2,6-Tolylenediamine
EINECS 212-513-9
1,3-Benzenediamine, 2-methyl-
2-methylbenzene-1,3-diamine
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
284.2±20.0 °C at 760 mmHg
[ Melting Point ]:
104-106 °C(lit.)
[ Molecular Formula ]:
C7H10N2
[ Molecular Weight ]:
122.168
[ Flash Point ]:
148.3±21.3 °C
[ Exact Mass ]:
122.084396
[ PSA ]:
52.04000
[ LogP ]:
0.15
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.636
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, strong acids.
[ Water Solubility ]:
60 g/L (15 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XS9750000
- CHEMICAL NAME :
- Toluene-2,6-diamine
- CAS REGISTRY NUMBER :
- 823-40-5
- BEILSTEIN REFERENCE NO. :
- 2079476
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C7-H10-N2
- MOLECULAR WEIGHT :
- 122.19
- WISWESSER LINE NOTATION :
- ZR CZ B1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Micronucleus test
- TYPE OF TEST :
- DNA inhibition
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 10 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 265,45,1992
Safety Information
[ Symbol ]:
GHS07, GHS08, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302 + H312-H317-H341-H411
[ Precautionary Statements ]:
P273-P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R21/22;R40;R43;R50/53
[ Safety Phrases ]:
S24-S36/37-S61
[ RIDADR ]:
UN 3077 9/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
XS9750000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Med. Lav. 103(5) , 361-71, (2012)
Despite its advantages over environmental monitoring, biological monitoring of exposure to 2,4-:2,6-toluene diisocyanate (TDI) mixtures is still underused. The present study was designed in order to e...
Occup. Environ. Med. 69(2) , 93-8, (2012)
Toluene diisocyanate (TDI) is used in the manufacturing process of polyurethane (PU) foams and is a potent inducer of occupational asthma. The objective of this study was to evaluate the correlation b...
Int. Arch. Occup. Environ. Health 78(6) , 459-66, (2005)
To develop a simple and sensitive GC-MS method for determining toluene-diamine (TDA) in urine and to apply the method for biological monitoring of workers exposed to toluene-diisocyanate (TDI).After a...