4-[[4-[4-(hydroxymethyl)-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile

Names

[ CAS No. ]:
823786-21-6

[ Name ]:
4-[[4-[4-(hydroxymethyl)-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile

[Synonym ]:
I14-9277
Benzonitrile,4-[[4-[[4-(hydroxymethyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]
4-[4-(4-hydroxymethyl-2,6-dimethylphenylamino)pyrimidin-2-ylamino]benzonitrile

Chemical & Physical Properties

[ Density]:
1.3g/cm3

[ Boiling Point ]:
601.8ºC at 760 mmHg

[ Molecular Formula ]:
C20H19N5O

[ Molecular Weight ]:
345.39800

[ Flash Point ]:
317.7ºC

[ Exact Mass ]:
345.15900

[ PSA ]:
97.09000

[ LogP ]:
3.43948

[ Index of Refraction ]:
1.67

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ETHYL 4-(2-(4-CYANOPHENYLAMINO)PYRIMIDIN-4-YLAMINO)-3,5-DIMETHYLBENZOATE
  • Ethyl 4-amino-3,5-dimethylbenzoate
  • 4-[(4-Chloro-2-pyrimidinyl)amino]benzonitrile

DownStream

  • Rilpivirine
  • 4-({4-[(4-Formyl-2,6-dimethylphenyl)amino]-2-pyrimidinyl}amino)be nzonitrile

Related Compounds

  • N4-cyclopropyl-N4-[1-(4-fluoro-2-methylbenzenesulfonyl)piperidin-4-yl]-N6,N6-dimethylpyrimidine-4,6-diamine
  • 3-Bromo-4-({1-[(2-chlorophenyl)methanesulfonyl]pyrrolidin-3-yl}oxy)pyridine
  • 2-(2,4-difluorophenyl)-N-(1-{thieno[3,2-d]pyrimidin-4-yl}azetidin-3-yl)acetamide
  • 3-(4-Chlorophenyl)-6-{4-[(2-methyl-1,3-thiazol-4-yl)methyl]piperazin-1-yl}pyridazine
  • 1-(4-{[5-(6-Methylpyrimidin-4-yl)-octahydropyrrolo[3,4-c]pyrrol-2-yl]sulfonyl}phenyl)pyrrolidine-2,5-dione
  • N-Methyl-N-[1-(3-pyridin-3-yl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)azetidin-3-yl]oxane-2-carboxamide
  • N-methyl-N-[1-(6-phenylpyridazin-3-yl)azetidin-3-yl]-2-(pyridin-3-yl)acetamide
  • 3-phenyl-N-(1-{thieno[3,2-d]pyrimidin-4-yl}azetidin-3-yl)propanamide
  • 2-phenoxy-N-(1-{thieno[3,2-d]pyrimidin-4-yl}azetidin-3-yl)acetamide
  • 5-[[4-[6-(3-Fluorophenyl)pyridazin-3-yl]piperazin-1-yl]methyl]-3-propan-2-yl-1,2,4-oxadiazole
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