2,2,6,6-tetramethyl-4 piperidone

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Names

[ CAS No. ]:
826-36-8

[ Name ]:
2,2,6,6-tetramethyl-4 piperidone

[Synonym ]:
2,2,6,6-tetramethyl-4-oxo-piperidine
4-Piperidinone, 2,2,6,6-tetramethyl-
2,2,6,6-tetramethyltetrahydro-4(1H)-pyridinone
Odoratine
2,2,6,6-Tetramethyl-4-piperidinone
IKh196
Triacetonamin
2,2,6,6-Tetramethyl-4-piperidone
2,2,6,6-tetramethyl-piperidinyl-4-one
Vincubina
TEMP
4-oxo-2,2,6,6-tetramethylpiperidine
2,2,6,6-tetramethyl-4 piperidone
triacetone amine
MFCD00005975
2,2,6,6-Tetramethylpiperidin-4-one
Tempidon
Vincubine
EINECS 212-554-2

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
205.6±15.0 °C at 760 mmHg

[ Melting Point ]:
59-61 °C

[ Molecular Formula ]:
C9H17NO

[ Molecular Weight ]:
155.237

[ Flash Point ]:
73.2±20.5 °C

[ Exact Mass ]:
155.131012

[ PSA ]:
29.10000

[ LogP ]:
1.32

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.427

[ Storage condition ]:
Refrigerator (+4°C)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TO0127900
CHEMICAL NAME :
4-Piperidone, 2,2,6,6-tetramethyl-
CAS REGISTRY NUMBER :
826-36-8
BEILSTEIN REFERENCE NO. :
0112665
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C9-H17-N-O
MOLECULAR WEIGHT :
155.27
WISWESSER LINE NOTATION :
T6N DVTJ B1 B1 F1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1539 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 28(5),53,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
385 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APPFAR Acta Poloniae Pharmaceutica (English Translation). Translation of APPHAX. (Warsaw, Poland) V.20-29, 1963-72. Discontinued. Volume(issue)/page/year: 24,652,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APPFAR Acta Poloniae Pharmaceutica (English Translation). Translation of APPHAX. (Warsaw, Poland) V.20-29, 1963-72. Discontinued. Volume(issue)/page/year: 24,652,1967 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7029 No. of Facilities: 13 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 264 (estimated) No. of Female Employees: 26 (estimated)

Safety Information

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S45-S36/37/39-S26-S22-S36/37

[ RTECS ]:
TO0127900

[ HS Code ]:
2933399090

Synthetic Route

Precursor & DownStream

Precursor

  • Phorone
  • Acetone
  • 1,2,2,6,6-Pentamethyl-4-piperidone
  • 2,2,6,6-Tetramethyl-4-piperidinol
  • 3-Methyl-2-butanone
  • 2,3,4,5-tetrahydro-2,2,4,4,6-pentamethylpyrimidine
  • 2-Butanone
  • Cyclohexanone
  • 2,6-diamino-2,6-dimethyl-heptan-4-one

DownStream

  • methyl 3-(2,2,6,6-tetramethyl-4-oxopiperidin-1-yl)prop-2-enoate
  • N-butyl-2,2,6,6-tetramethylpiperidin-4-amine
  • 2,2,6,6-Tetramethyl-4-piperidinol
  • 3-amino-2,2,5,5-tetramethyl-1-pyrrolidinyloxy
  • 4-Amino-2,2,6,6-tetramethylpiperidine
  • 7,7,9,9-tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane-2-methanol
  • 1,2,2,6,6-Pentamethyl-4-piperidone
  • 2,2,6,6-Tetramethyl-4-piperidone Oxime
  • 4-hydroxy-2,2,6,6-tetramethylpiperidine-4-carbonitrile
  • 3,5-dibromo-2,2,6,6-tetramethylpiperidin-4-one,hydrobromide

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 1H-perdeutero-2,2,6,6-tetramethyl-4-piperidone
  • 2,4-dinitrophenylhydrazone of 2,2,6,6-tetramethyl-4-piperidone-1-oxyl
  • 7,7,9,9-tetramethyl-1,4-dioxa-8-azaspiro[4.5]decane
  • (2,2,6,6-tetramethyl-4-oxopiperidin-1-yl) acetate
  • 2,2,6,6-tetramethyl-4-octadecoxypiperidine
  • 2,2,6,6-tetramethyl-4-(3-picrylamino)piperidine N-oxide
  • 1-(6-Fluoro-1H-indol-2-yl)ethanone
  • 1-(5-Fluoro-1H-indol-6-yl)ethan-1-one
  • 2-Amino-1-(1-benzofuran-3-yl)ethan-1-ol
  • 1-(5-Methylpyridin-3-yl)cyclopropane-1-carboxylic acid
  • 2-Amino-1-(2,3-dihydro-1-benzofuran-7-yl)ethan-1-one
  • 6-Hydroxy-1-methyl-2,3-dihydroindole-5-carbaldehyde
  • 2-(2-Methylpyrazolo[1,5-a]pyrimidin-6-yl)ethan-1-ol
  • 2-Amino-2-{imidazo[1,2-a]pyridin-3-yl}ethan-1-ol
  • 2-Amino-2-(imidazo[1,2-a]pyridin-8-yl)ethan-1-ol
  • 2-amino-2-(1H-indazol-7-yl)ethan-1-ol
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