Flurithromycin
Suppliers
Names
[ CAS No. ]:
82664-20-8
[ Name ]:
Flurithromycin
[Synonym ]:
fluritromicina
Huritromicina(sp)
8-fluoro-erythromyci
cl-932
8-fluoroerythromycin
P-0501-A
C1-932
(8S)-8-fluoroerythromycin A
Chemical & Physical Properties
[ Density]:
1.22g/cm3
[ Boiling Point ]:
814.6ºC at 760 mmHg
[ Molecular Formula ]:
C37H66FNO13
[ Molecular Weight ]:
751.91700
[ Flash Point ]:
446.5ºC
[ Exact Mass ]:
751.45200
[ PSA ]:
193.91000
[ LogP ]:
1.87770
[ Index of Refraction ]:
1.531
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KF4800000
- CHEMICAL NAME :
- Erythromycin, 8-fluoro-
- CAS REGISTRY NUMBER :
- 82664-20-8
- LAST UPDATED :
- 199310
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C37-H66-F-N-O13
- MOLECULAR WEIGHT :
- 752.04
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 12,214,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 12,214,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 8100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 37,84-108,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 790 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 37,84-108,1984
Safety Information
[ Hazard Codes ]:
F
[ Risk Phrases ]:
10
[ Safety Phrases ]:
16