2,6-Dichloro-5-fluoronicotinic acid

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Names

[ CAS No. ]:
82671-06-5

[ Name ]:
2,6-Dichloro-5-fluoronicotinic acid

[Synonym ]:
2,6-dichloro-5-fluoropyridine-3-carboxylic acid
3-Pyridinecarboxylic acid, 2,6-dichloro-5-fluoro-
2,6-Dichloro-5-fluoronicotinic acid
MFCD00799517

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
335.3±37.0 °C at 760 mmHg

[ Melting Point ]:
152-155 °C(lit.)

[ Molecular Formula ]:
C6H2Cl2FNO2

[ Molecular Weight ]:
209.99

[ Flash Point ]:
156.6±26.5 °C

[ Exact Mass ]:
208.944656

[ PSA ]:
50.19000

[ LogP ]:
1.53

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.580

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate
  • Methyl 5-fluoro-2,6-dihydroxynicotinate
  • 2,6-Dichloro-5-fluoronicotinonitrile
  • 2,6-Dichloro-5-fluoronicotinamide
  • 2-cyanopyridine

DownStream

  • ethyl 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
  • Tosufloxacin pharmaceutical intermediate
  • 2-Chloro-5-fluoronicotinic acid
  • 5-Fluoronicotinic acid
  • 2-Chloro-5-fluoronicotinonitrile
  • ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate
  • 2,6-dichloro-5-fluoronicotinoyl chloride
  • Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate
  • Ethyl 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
  • 2,6-Dichloro-5-fluoro-4-methylnicotinic acid

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

The adhesive properties of pyridine-terminated self-assembled monolayers. Bowen J, et al.

Thin Solid Films 517(13) , 3806-3812, (2009)

Yaws CL.

The Yaws Handbook of Physical Properties for Hydrocarbons and Chemicals 2nd ed.,, (2015), 88


More Articles

Related Compounds

  • 2,6-dichloro-5-fluoronicotinic acid
  • 2,6-dichloro-5-fluoronicotinic acid chloride
  • 2,6-Dichloro-5-fluoro-4-methylnicotinic acid
  • 2,6-dichloro-4-ethyl-5-fluoronicotinic acid
  • 4,6-Dichloro-5-fluoronicotinic acid
  • 2,6-Dichloro-5-quinolinecarboxylic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • N-[2-(Aminomethyl)phenyl]-4-(cyclohexyloxy)butanamide
  • (2R,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid benzyl ester
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • Methyl 5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolane 4-carboxylate
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde