5-Chloroindole-3-carboxaldehyde

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Names

[ CAS No. ]:
827-01-0

[ Name ]:
5-Chloroindole-3-carboxaldehyde

[Synonym ]:
1H-Indole-3-carboxaldehyde, 5-chloro-
5-CHLOROINDOLE-3-ALDEHYDE
5-chloro-3-formyl-indole
5-chloro-indole-3-carboxaldehyde
5-chloroindole-3-carboxyaldehyde
5-Chloro-indole-3-carbaldehyde
5-CHLORO-1H-INDOLE-3-CARBOXALDEHYDE
5-Chloro-1H-indole-3-carbaldehyde
MFCD00175291
5-chloro-3-indolecarboxaldehyde
5-Chloroindole-3-carboxaldehyde

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
373.4±22.0 °C at 760 mmHg

[ Melting Point ]:
213-216 °C(lit.)

[ Molecular Formula ]:
C9H6ClNO

[ Molecular Weight ]:
179.603

[ Flash Point ]:
179.6±22.3 °C

[ Exact Mass ]:
179.013794

[ PSA ]:
32.86000

[ LogP ]:
2.47

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.732

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39-S22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Precursor

  • 5-Chloroindole
  • 5-Bromoindole-3-carboxaldehyde
  • N-Methylaniline
  • N,N-Dimethylformamide
  • 5-Chloroindole-2-carboxylic acid

DownStream

  • 2-(5-Chloro-1H-indol-3-yl)ethanamine hydrochloride
  • 5-chloro-3-methyl-1H-indole
  • 5-Chloro-1H-indole-3-carboxylic acid
  • 3-(5-chloro-1H-indol-3-yl)propanoic acid

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis and antifungal activity of novel streptochlorin analogues.

Eur. J. Med. Chem. 92 , 776-83, (2015)

Streptochlorin, first isolated as a new antibiotic in 1988 from the lipophilic extracts of the mycelium of a Streptomyces sp, is an indole natural products with a variety of biological activities. Bas...

Electrochemical behavior of indole-3-carboxaldehyde izonicotinoyl hydrazones: discussion on possible biological behavior Shirinzadeh H, et al.

Comb. Chem. High Throughput Screen 13(7) , 619-627, (2010)

2′-[(5-Chloro-1H-indol-3-yl) methylene]-2-(1H-indol-3-yl) acetohydrazide. Ali HM, et al.

Acta Crystallogr. Sect. E Struct. Rep. Online 63(4) , o1807-o1808, (2007)


More Articles


Related Compounds

  • 2-methyl-5-chloroindole-3-carboxaldehyde
  • 4-Chloroindole-3-carboxaldehyde
  • 3-acetyloxy-5-chloroindole
  • 3-tert-Butyl-5-chloroindole
  • 1-(4-Chlorobenzyl)-2-chloroindole-3-carboxaldehyde
  • 5-Chloro-1H-indole-3-carboxylic acid