PD0332991 HCl

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Names

[ CAS No. ]:
827022-32-2

[ Name ]:
PD0332991 HCl

[Synonym ]:
Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-, hydrochloride (1:1)
Palbociclib hydrochloride
UNII:BKC4F3Q5XL
Palbociclib HCl
6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one,hydrochloride
6-Acetyl-8-cyclopentyl-5-methyl-2-{[5-(1-piperazinyl)-2-pyridinyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride (1:1)
PD 0332991 HCl
PD0332991
PD0332991.HCl
Palbociclib
Palbociclib (hydrochloride)

Chemical & Physical Properties

[ Boiling Point ]:
727ºC at 760 mmHg

[ Molecular Formula ]:
C24H30ClN7O2

[ Molecular Weight ]:
483.994

[ Flash Point ]:
393.5ºC

[ Exact Mass ]:
483.214966

[ PSA ]:
105.04000

[ LogP ]:
4.23460

[ Storage condition ]:
-20°C

Safety Information

[ HS Code ]:
29399990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-{6-[8-cyclopentyl-6-(1-ethoxyvinyl)-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-ylamino]pyridin-3-yl}piperazine-1-carboxylic acid tert-butyl ester

DownStream

  • palbociclib

Related Compounds

  • Difelikefalin HCl
  • EPZ020411 HCl
  • Pazopanib HCl (GW786034 HCl)
  • OCTENIDINE HCl
  • PD153035 HCl
  • ALAPROCLATE HCL
  • methyl 4-(((4-hydroxytetrahydro-2H-pyran-4-yl)methyl)carbamoyl)benzoate
  • N-((4-hydroxytetrahydro-2H-pyran-4-yl)methyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide
  • N-((4-hydroxytetrahydro-2H-pyran-4-yl)methyl)-3-(4-methoxyphenyl)propanamide
  • 2-(ethylthio)-N-((4-hydroxytetrahydro-2H-pyran-4-yl)methyl)benzamide
  • N-[(4-hydroxyoxan-4-yl)methyl]-2-(naphthalen-1-yl)acetamide
  • N-((4-hydroxytetrahydro-2H-pyran-4-yl)methyl)-2-(trifluoromethyl)benzamide
  • 5-bromo-N-((4-hydroxytetrahydro-2H-pyran-4-yl)methyl)furan-2-carboxamide
  • N-((4-hydroxytetrahydro-2H-pyran-4-yl)methyl)-7-methoxybenzofuran-2-carboxamide
  • N-((4-hydroxytetrahydro-2H-pyran-4-yl)methyl)-1-(thiophen-2-yl)cyclopentanecarboxamide
  • N-((4-hydroxytetrahydro-2H-pyran-4-yl)methyl)-[1,1'-biphenyl]-4-carboxamide
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