PD0332991 HCl

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Names

[ CAS No. ]:
827022-32-2

[ Name ]:
PD0332991 HCl

[Synonym ]:
Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-, hydrochloride (1:1)
Palbociclib hydrochloride
UNII:BKC4F3Q5XL
Palbociclib HCl
6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one,hydrochloride
6-Acetyl-8-cyclopentyl-5-methyl-2-{[5-(1-piperazinyl)-2-pyridinyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride (1:1)
PD 0332991 HCl
PD0332991
PD0332991.HCl
Palbociclib
Palbociclib (hydrochloride)

Chemical & Physical Properties

[ Boiling Point ]:
727ºC at 760 mmHg

[ Molecular Formula ]:
C24H30ClN7O2

[ Molecular Weight ]:
483.994

[ Flash Point ]:
393.5ºC

[ Exact Mass ]:
483.214966

[ PSA ]:
105.04000

[ LogP ]:
4.23460

[ Storage condition ]:
-20°C

Safety Information

[ HS Code ]:
29399990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-{6-[8-cyclopentyl-6-(1-ethoxyvinyl)-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-ylamino]pyridin-3-yl}piperazine-1-carboxylic acid tert-butyl ester

DownStream

  • palbociclib

Related Compounds

  • Difelikefalin HCl
  • EPZ020411 HCl
  • Pazopanib HCl (GW786034 HCl)
  • OCTENIDINE HCl
  • PD153035 HCl
  • ALAPROCLATE HCL
  • 6-Oxo-2-{spiro[2.2]pentan-1-yl}-1,6-dihydropyrimidine-5-carboxylic acid
  • Methyl 6-oxo-2-{spiro[2.2]pentan-1-yl}-1,6-dihydropyrimidine-5-carboxylate
  • 2-(2-Ethyl-1,3-thiazol-4-yl)pyrimidine-4-carboxylic acid
  • 2-(1-Methylpiperidin-2-yl)pyrimidine-4-carboxylic acid
  • 5-Methyl-2-(1,2,2-trimethylcyclopropyl)pyrimidine-4-carboxylic acid
  • 2-[(2,2-Difluorocyclopropyl)methyl]-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid
  • 5-Methyl-2-(oxan-2-yl)pyrimidine-4-carboxylic acid
  • 2-(Azetidin-1-yl)pyrimidine-4-carboxylic acid
  • [(3S)-2,2-dimethylpentan-3-yl][(4-fluorophenyl)methyl]amine
  • [(3S)-2,2-dimethylpentan-3-yl][(2-fluorophenyl)methyl]amine
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