Nefazodone

Suppliers

Names

[ CAS No. ]:
83366-66-9

[ Name ]:
Nefazodone

[Synonym ]:
[14C]-Nefazodone hydrochloride
Nefazodonum
Nefazodonum [Latin]
2-[3-[4-(3-chlorophenyl)-1-piperazinyl]-propyl-]5-ethyl-2,4-dihydro-4-(2-phenoxy-ethyl)-3H-1,2,4-triazol-3-one
2-<3-<4-(3-chlorophenyl)-1-piperazinyl>propyl>-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazolin-3-one
Nefazodone Hcl
2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazol-3-one
Nefazodona
Nefazodone (INN)
Nefazodona [Spanish]
2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one
UNII-59H4FCV1TF
MFCD00935760

Chemical & Physical Properties

[ Melting Point ]:
180-182°C

[ Molecular Formula ]:
C25H32ClN5O2

[ Molecular Weight ]:
470.00700

[ Exact Mass ]:
469.22400

[ PSA ]:
55.53000

[ LogP ]:
3.55480

[ Water Solubility ]:
DMSO: ~11 mg/mL at 60 °C

Safety Information

[ Safety Phrases ]:
S22-S24/25

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • EPT
  • 1-(3-chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride
  • 2-phenoxyethylisocyanate
  • 3-phenoxypropionyl hydrazide hydrochloride

DownStream

Related Compounds

  • Nefazodone hydrochloride
  • Methoxymethoxy Nefazodone
  • Hydroxy Nefazodone Dihydrochloride
  • Hydroxy Nefazodone-d6 hydrochloride
  • piperazine hydrochloride; ( Intermediates for Nefazodone, Etoperidone and Trazadone)
  • 3-{1-[4-(morpholin-4-ylmethyl)phenyl]-1H-1,2,3-triazol-4-yl}-1H-indazole-5-carboxylic acid
  • tert-butyl 4-[4-({4-[4-(1H-indazol-3-yl)-1H-1,2,3-triazol-1-yl]benzoyl}amino)-1H-pyrazol-1-yl]piperidine-1-carboxylate
  • 2-(1-Ethyl-3-methylpyrazol-4-yl)-4-phenyl-1,3-thiazole-5-carboxylic acid
  • 1h-Pyrazole-3-carboxamide,4-[3-(hydroxymethyl)phenyl]-1-[(4-methoxyphenyl)methyl]-n-phenyl-
  • 2-[[2-(Ethylamino)ethyl](1-methylethyl)amino]ethanol
  • 2-(2-Fluorophenyl)butanenitrile
  • N-[4-(1-aminoethyl)-2,6-difluorophenyl]methanesulfonamide
  • 6-(benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid
  • 4-[(2-Amino-2-oxoethyl)sulfinyl]benzoic acid
  • 4-(Cyanomethanesulfinyl)benzoic acid
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