7H-Pyrrolo[2,3-d]pyrimidine-5-carboxamide,4-amino-6-bromo-7-[2-O-[(4-methylphenyl)sulfonyl]-b-D-ribofuranosyl]-

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Names

[ CAS No. ]:
83379-26-4

[ Name ]:
7H-Pyrrolo[2,3-d]pyrimidine-5-carboxamide,4-amino-6-bromo-7-[2-O-[(4-methylphenyl)sulfonyl]-b-D-ribofuranosyl]-

[Synonym ]:
6-bromo-2'-O-tosylsangivamycin

Chemical & Physical Properties

[ Density]:
1.97g/cm3

[ Boiling Point ]:
872.4ºC at 760 mmHg

[ Molecular Formula ]:
C19H20BrN5O7S

[ Molecular Weight ]:
542.36000

[ Flash Point ]:
481.4ºC

[ Exact Mass ]:
541.02700

[ PSA ]:
201.26000

[ LogP ]:
2.57030

[ Index of Refraction ]:
1.789

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 7H-Pyrrolo[2,3-d]pyrimidine-5-carbonitrile,4-amino-6-bromo-7-[2-O-[(4-methylphenyl)sulfonyl]-b-D-ribofuranosyl]-
  • 5-amino-8-bromo-9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4,9-triazabicyclo[4.3.0]nona-1,3,5,7-tetraene-7-carboxamide; dibutyltin
  • Tosyl chloride
  • 7H-Pyrrolo[2,3-d]pyrimidine-5-carbonitrile,4-amino-6-bromo-7-[2,3-O-(dibutylstannylene)-b-D-ribofuranosyl]-

DownStream

  • 4-Amino-7-hydroxy-8-(hydroxymethyl)-6a,7,8,9a-tetrahydrofuro(2,3:4,5)(1,3)thiazolo(2,3:5,1)pyrrolo(2,3-d)pyrimidine-5-carboxamide
  • 4-Amino-7-(2-deoxy-beta-D-erythro-pentofuranosyl)-7H-pyrrolo(2,3-d)pyrimidine-5-carboxamide

Related Compounds

  • 3-cyclopropyl-3-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]butanoic acid
  • 3-cyclopropyl-3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pent-4-ynamido]butanoic acid
  • 3-cyclopropyl-3-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanamido]butanoic acid
  • 3-cyclopropyl-3-{[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}butanoic acid
  • 3-cyclopropyl-3-({1-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopropyl}formamido)butanoic acid
  • 4-Amino-1-propan-2-yl-5-(2-propan-2-yl-1,3-thiazol-5-yl)pyrrolidin-2-one
  • 1-[3-cyclopropyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoyl]-3-hydroxyazetidine-3-carboxylic acid
  • 2-[3-cyclopropyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-propylbutanamido]acetic acid
  • (9H-fluoren-9-yl)methyl N-[2-(3,5-dichlorophenyl)-1-hydroxypropan-2-yl]carbamate
  • 2-[3-cyclopropyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-methylbutanamido]butanoic acid
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