Mifamurtide

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Names

[ CAS No. ]:
83461-56-7

[ Name ]:
Mifamurtide

[Synonym ]:
Mifamurtide
muramyl tripeptide phosphatidylethanolamine
(2R,5S,8R,13S,22R)-2-{[(3R,4R,5S,6R)-3-Acetamido-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}-8-carbamoyl-19-hydroxy-5,13-dimethyl-19-oxido-3,6,11,14,25-pentaoxo-18,20,24-trioxa-4,7,12 ;,15-tetraaza-19λ-phosphatetracontan-22-yl hexadecanoate
N-Acetylmuramyl-alanyl-isoglutaminyl-alanyl-sn-glycero-3-phosphoethano lamine

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Molecular Formula ]:
C59H109N6O19P

[ Molecular Weight ]:
1237.499

[ Exact Mass ]:
1236.748535

[ PSA ]:
385.91000

[ LogP ]:
10.98

[ Index of Refraction ]:
1.530

[ Storage condition ]:
2-8℃

Safety Information

Articles

Muramyl tripeptide (mifamurtide) for the treatment of osteosarcoma.

Expert Rev. Anticancer Ther. 9(8) , 1035-49, (2009)

Osteosarcoma is an ultraorphan disease. There are approximately 1000 new patients diagnosed with osteosarcoma each year in the USA and Europe. Current treatment for osteosarcoma utilizes multiagent ch...

Imunomodulative effect of liposomized muramyltripeptide phosphatidylethanolamine (L-MTP-PE) on mice with alveolar echinococcosis and treated with albendazole.

Parasitol. Res. 103(4) , 919-29, (2008)

The effect of liposomized muramyltripeptide phosphatidylethanolamine (L-MTP-PE) administered separately or with anthelmintic albendazole (ABZ) on cellular immunity of mice with alveolar echinococcosis...

In vitro and in vivo enhancement of canine pulmonary alveolar macrophage cytotoxic activity against canine osteosarcoma cells.

Cancer Biother. Radiopharm. 14(2) , 121-8, (1999)

The combination of chemotherapy with immunotherapy may offer an advantage over either therapy alone and provide a greater potential for total tumor eradication. Monocyte/macrophage-mediated tumor cell...


More Articles


Related Compounds

  • Mifamurtide
  • Mifamurtide sodium
  • 2-(4-methoxybenzamido)-N-(pyridin-4-ylmethyl)-5,6-dihydro-4H-cyclopenta[d]thiazole-4-carboxamide
  • delta1-Cortienic Acid Methyl Ester
  • 2,4-Dichloro-1-(2-isothiocyanatoethyl)benzene
  • 3-((4-methoxyphenyl)sulfonyl)-1-propylquinolin-4(1H)-one
  • N-2-Benzothiazolyl-N-ethyl-I(2)-alanine
  • Silane, [[(1R,6R)-6-azido-3-cyclohexen-1-yl]oxy]trimethyl-, rel-
  • 6-trifluoromethyl-3-(piperidin-4-yl)-1H-indole
  • (Hexahydro-3-hydroxy-1H-azepin-1-yl)phenylmethanone
  • 3-Chloro-5-cholestene
  • (R)-2-(2'-(Diphenylphosphanyl)-[1,1'-binaphthalen]-2-yl)-4,4-dimethyl-4,5-dihydrooxazole
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