UNII:SHY3J1BBQ6
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Names
[ CAS No. ]:
83463-62-1
[ Name ]:
UNII:SHY3J1BBQ6
[Synonym ]:
Acetonitrile, 2-bromo-2-chloro-
BROMOCHLOROACETONITRILE
Bromo(chloro)acetonitrile
UNII:SHY3J1BBQ6
2-bromo-2-chloroacetonitrile
Chemical & Physical Properties
[ Density]:
1.9±0.1 g/cm3
[ Boiling Point ]:
121.1±20.0 °C at 760 mmHg
[ Molecular Formula ]:
C2HBrClN
[ Molecular Weight ]:
154.393
[ Flash Point ]:
27.1±21.8 °C
[ Exact Mass ]:
152.898087
[ PSA ]:
23.79000
[ LogP ]:
1.23
[ Vapour Pressure ]:
14.8±0.2 mmHg at 25°C
[ Index of Refraction ]:
1.507
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AL8010000
- CHEMICAL NAME :
- Acetonitrile, bromochloro-
- CAS REGISTRY NUMBER :
- 83463-62-1
- LAST UPDATED :
- 199607
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C2-H-Br-Cl-N
- MOLECULAR WEIGHT :
- 154.40
- WISWESSER LINE NOTATION :
- NCYGE
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2400 mg/kg/2W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 825 mg/kg
- SEX/DURATION :
- female 7-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 845 mg/kg
- SEX/DURATION :
- female 6-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - other effects
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 585 mg/kg
- SEX/DURATION :
- female 6-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 65 mg/kg
- SEX/DURATION :
- female 6-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 4200 nmol/L
- REFERENCE :
- FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 5,1065,1985 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,269,1991 IARC Cancer Review:Human No Available Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,269,1991 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,269,1991
Safety Information
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R23/24/25;R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 1760
[ RTECS ]:
AL8010000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2926909090
Synthetic Route
Customs
[ HS Code ]: 2926909090
[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%