Regorafenib (Hydrochloride)

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Names

[ CAS No. ]:
835621-07-3

[ Name ]:
Regorafenib (Hydrochloride)

[Synonym ]:
CS-0725
4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrochloride (1:1)
2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-, hydrochloride (1:1)
Regorafenib Hydrochloride
Regorafenib (Hydrochloride)

Chemical & Physical Properties

[ Molecular Formula ]:
C21H16Cl2F4N4O3

[ Molecular Weight ]:
519.276

[ Exact Mass ]:
518.053589

[ PSA ]:
95.84000

[ LogP ]:
6.96830

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Regorafenib (BAY 73-4506)
  • 3-Fluoro-4-nitrophenol
  • 4-Amino-3-fluorophenol
  • 4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide

DownStream

Related Compounds

  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • Elacridar hydrochloride
  • dodecylamine hydrochloride
  • Azetidine, hydrochloride, homopolymer (9CI)
  • N-(4-(4-(2-methoxyethyl)-5-oxo-4,5-dihydro-1H-tetrazol-1-yl)phenyl)-2-phenoxyacetamide
  • N-cyclopropyl-2-(4-(2-(methylthio)benzamido)phenyl)-2H-tetrazole-5-carboxamide
  • 3,4-Dibromo-5-cyclopropoxypyridine
  • 3,5-Dichloro-4-cyclopropoxypyridine
  • 2-Chloro-5-cyclopropoxypyridine-4-sulfonamide
  • N-cyclopropyl-2-(4-(2,4-difluorobenzamido)phenyl)-2H-tetrazole-5-carboxamide
  • 2-(4-(2-(2-chlorophenyl)acetamido)phenyl)-N-cyclopropyl-2H-tetrazole-5-carboxamide
  • (R)-Methyl 3-amino-2-(1H-imidazol-5-YL)propanoate
  • 4-[2-(propan-2-yl)-2H-tetrazol-5-yl]-N-(pyridin-3-ylmethyl)benzamide
  • N-cyclopropyl-2-(4-(2-(3-methoxyphenyl)acetamido)phenyl)-2H-tetrazole-5-carboxamide