Regorafenib (Hydrochloride)

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Names

[ CAS No. ]:
835621-07-3

[ Name ]:
Regorafenib (Hydrochloride)

[Synonym ]:
CS-0725
4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrochloride (1:1)
2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-, hydrochloride (1:1)
Regorafenib Hydrochloride
Regorafenib (Hydrochloride)

Chemical & Physical Properties

[ Molecular Formula ]:
C21H16Cl2F4N4O3

[ Molecular Weight ]:
519.276

[ Exact Mass ]:
518.053589

[ PSA ]:
95.84000

[ LogP ]:
6.96830

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Regorafenib (BAY 73-4506)
  • 3-Fluoro-4-nitrophenol
  • 4-Amino-3-fluorophenol
  • 4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide

DownStream

Related Compounds

  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • Elacridar hydrochloride
  • dodecylamine hydrochloride
  • Azetidine, hydrochloride, homopolymer (9CI)
  • 2-(3-Fluorobenzoyl)-5-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-octahydropyrrolo[3,4-c]pyrrole
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 2-(((1H-benzo[d]imidazol-2-yl)thio)methyl)-3-methyl-4-nitropyridine 1-oxide
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • Lenalidomide 4'-PEG1-amine (dihydrochloride)
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde