Regorafenib (Hydrochloride)

Suppliers

Names

[ CAS No. ]:
835621-07-3

[ Name ]:
Regorafenib (Hydrochloride)

[Synonym ]:
CS-0725
4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide hydrochloride (1:1)
2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-, hydrochloride (1:1)
Regorafenib Hydrochloride
Regorafenib (Hydrochloride)

Chemical & Physical Properties

[ Molecular Formula ]:
C21H16Cl2F4N4O3

[ Molecular Weight ]:
519.276

[ Exact Mass ]:
518.053589

[ PSA ]:
95.84000

[ LogP ]:
6.96830

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Regorafenib (BAY 73-4506)
  • 3-Fluoro-4-nitrophenol
  • 4-Amino-3-fluorophenol
  • 4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide

DownStream

Related Compounds

  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • Elacridar hydrochloride
  • dodecylamine hydrochloride
  • Azetidine, hydrochloride, homopolymer (9CI)
  • 4-Chloro-6-(furan-2-ylmethoxy)pyrimidine
  • 4-(3-Furanyl)-6-methylquinoline
  • 2-(3,5-Difluorophenyl)ethanethioamide
  • 1H-Pyrazole-3-carboxylic acid, 4-(5-(3-(ethoxycarbonyl)-5-hydroxy-1-(tetrahydro-3-thienyl)-1H-pyrazol-4-yl)-2,4-pentadienylidene)-4,5-dihydro-5-oxo-1-(tetrahydro-3-thienyl)-, ethyl ester, S,S,S',S'-tetraoxide
  • 7,8,13,14-Tetrachloroperyleno[2,3-c:4,5-c']difuran-1,3,4,6-tetraone
  • (6S)-4-Methoxybenzyl 3-(chloromethyl)-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • 7,5-Dichloro-7aH-indole
  • tert-Butyl (2-(4-bromo-1-(2-hydroxyethyl)-1H-benzo[d]imidazol-2-yl)ethyl)carbamate
  • Tert-butyl 4-(1-ethoxy-1-oxopropan-2-yl)-1,4-diazepane-1-carboxylate
  • US10272074, Example 457
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