L-Buthionine (S,R)-sulfoximine

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Names

[ CAS No. ]:
83730-53-4

[ Name ]:
L-Buthionine (S,R)-sulfoximine

[Synonym ]:
L-BUTHIONINESULPHOXIMINE
L-BUTHIONINE-S,R-SULPHOXIMINE
Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-, (2S)-
L-BUTHIONINE-SULFOXIMINE
L-BUTHIONINE-[S,R]-SULFOXIME
MFCD00067000
(2S)-2-Amino-4-(S-butylsulfonimidoyl)butanoic acid
dl-S-(n-butyl)-homocystein-DR-sulfoximine
buthionine-<S,R>-sulfoximine
L-Buthionine (S,R)-sulfoximine
D-Buthionine Sulfoximine
D,L-buthionine-(S,R)-sulfoximine
Buthionine sulfoximine
L-BUTHIONINE (R,S)-SULFOXIMINE
L-BSO
DL-buthionine-(S,-R)-sulphoximine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
382.3±52.0 °C at 760 mmHg

[ Melting Point ]:
224-228ºC (dec.)

[ Molecular Formula ]:
C8H18N2O3S

[ Molecular Weight ]:
222.305

[ Flash Point ]:
185.0±30.7 °C

[ Exact Mass ]:
222.103806

[ PSA ]:
112.62000

[ LogP ]:
0.22

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.538

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EK7713440
CHEMICAL NAME :
Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-, (2S)-
CAS REGISTRY NUMBER :
83730-53-4
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H18-N2-O3-S
MOLECULAR WEIGHT :
222.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
3552 mg/kg
SEX/DURATION :
female 10-11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - Central Nervous System

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Human Lung
DOSE/DURATION :
10 mmol/L
REFERENCE :
CBTOE2 Cell Biology and Toxicology. (Princeton Scientific Pub., Inc., 301 N. Harrison St., CN 5279, Princeton, NJ 08540) V.1- 1984- Volume(issue)/page/year: 7,249,1991

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22;S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
EK7713440

[ HS Code ]:
2925290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • D,L-Buthionine

DownStream

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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Related Compounds

  • DL-Buthionine (S,R)-sulfoximine
  • D-Buthionine-(S,R)-sulfoximine
  • L-Methionine [S]-Sulfoximine
  • L-Alanine, 3-[[S(R)]-S-methylsulfonimidoyl]- (9CI)
  • L-S-(acetamidomethyl)-Nα-t-butoxycarbonyl-4'-mercaptophenylalanine
  • l-s-t-butylcysteine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • Ethyl 2-((2-aminoethyl)thio)acetate
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 9H-fluoren-9-ylmethyl 4-[(4-carbonochloridoylphenyl)methyl]piperidine-1-carboxylate
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 2-(Phenylsulfonyl)-1,2,3,4-tetrahydroisoquinolin-7-amine
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde