Dienestrol
Suppliers
Names
[ CAS No. ]:
84-17-3
[ Name ]:
Dienestrol
[Synonym ]:
Retalon
Oestrora
Dinestrol
MFCD00050983
Isodienoestrol
Agaldog
Sexadien
Estroral
Dienoestrol
EINECS 201-519-7
Dinovex
Teserene
Restrol
2,4-Hexadiene, 3,4-bis(4-hydroxyphenyl)-
Chemical & Physical Properties
[ Density]:
1.129 g/cm3
[ Boiling Point ]:
395.4ºC at 760 mmHg
[ Melting Point ]:
229ºC
[ Molecular Formula ]:
C18H18O2
[ Molecular Weight ]:
266.33400
[ Flash Point ]:
181.4ºC
[ Exact Mass ]:
266.13100
[ PSA ]:
40.46000
[ LogP ]:
4.60460
[ Index of Refraction ]:
1.4800 (estimate)
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SL0580000
- CHEMICAL NAME :
- Phenol, 4,4'-(diethylideneethylene)di-
- CAS REGISTRY NUMBER :
- 84-17-3
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C18-H18-O2
- MOLECULAR WEIGHT :
- 266.36
- WISWESSER LINE NOTATION :
- QR DYU2&YU2&R DQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 40 ug/kg
- SEX/DURATION :
- female 3 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- TYPE OF TEST :
- Unscheduled DNA synthesis
MUTATION DATA
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Rodent - hamster Fibroblast
- DOSE/DURATION :
- 75 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 171,31,1986 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,278,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83633 No. of Facilities: 124 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 2882 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83633 No. of Facilities: 9 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 166 (estimated) No. of Female Employees: 105 (estimated)
Safety Information
[ Symbol ]:
GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H350-H361
[ Precautionary Statements ]:
P201-P280-P308 + P313
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R40
[ Safety Phrases ]:
S22;S24/25
[ RIDADR ]:
2811.0
[ WGK Germany ]:
3
[ RTECS ]:
SL0580000
[ Hazard Class ]:
6.1
Articles
J. Chromatogr. A. 1368 , 18-25, (2014)
A modified Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) method based on the dispersive solid-phase extraction (dSPE) combined with high performance liquid chromatography (HPLC) was develo...
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 957 , 7-13, (2014)
• A method based on packed-fiber solid-phase extraction (PF SPE) has been established for the determination of three estrogenic stilbenes in dairy products. • Samples were pretreated with PF SPE using...
J. Chromatogr. A. 1356 , 54-63, (2014)
A method for analyzing 26 types of steroids in egg matrix was developed. The method used liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) in electrospray ionization mode (ESI). T...