4-Methoxy-1-naphthol

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Names

[ CAS No. ]:
84-85-5

[ Name ]:
4-Methoxy-1-naphthol

[Synonym ]:
EINECS 201-566-3
4-methoxynaphthalen-1-ol
MFCD00003976
1-Naphthalenol, 4-methoxy-
1-Naphthol, 4-methoxy-
4-Methoxy-1-naphthol

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
350.1±15.0 °C at 760 mmHg

[ Melting Point ]:
126-129 °C(lit.)

[ Molecular Formula ]:
C11H10O2

[ Molecular Weight ]:
174.196

[ Flash Point ]:
228.6±5.3 °C

[ Exact Mass ]:
174.068085

[ PSA ]:
29.46000

[ LogP ]:
2.54

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.641

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2909500000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,1,4,4-Tetramethoxy-1,4-dihydronaphthalene
  • 1-Methoxynapthalene
  • Methanol
  • 1,4-naphthoquinone
  • 4-Methoxy-1-naphthaldehyde
  • BENZOHYDROQUINONE
  • Dimethyl sulfate
  • Methyl 2-bromobenzoate

DownStream

  • (+/-)-4-hydroxypropranolol, hydrochloride
  • 4-Methoxy-2-phenylazo-1-naphthol
  • Beta-Lapachone
  • alpha-Lapachone
  • Dihydrolapachenole
  • Menadione
  • 1-Methoxynapthalene
  • 1,4-naphthoquinone
  • 2-(1,4-dioxonaphthalen-2-yl)naphthalene-1,4-dione

Customs

[ HS Code ]: 2909500000

[ Summary ]:
2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Synthesis and identification of 3-(4-hydroxy-1-naphthoxy)lactic acid as a metabolite of propranolol in the rat, in man, and in the rat liver 9000 g supernatant fraction.

Drug Metab. Dispos. 14(2) , 202-7, (1986)

The formation of 3-(4-hydroxy-1-naphthoxy)lactic acid (4-HO-NLA) from propranolol was investigated. Authentic 4-HO-NLA was synthesized from 4-methoxy-1-naphthol using methods previously used for prepa...


More Articles

Related Compounds

  • 3-Brom-4-methoxy-1-naphthol
  • 2-acetyl-4-methoxy-1-naphthol
  • 3-acetyl-4-methoxy-1-naphthol
  • 2-Benzyl-4-methoxy-1-naphthol
  • 8-Benzyloxy-4-methoxy-1-naphthol
  • 5,8-Dichlor-4-methoxy-1-naphthol
  • 2-(4-Chloro-3-methoxyphenyl)-2-methoxypropan-1-amine
  • 3-(4-Chloro-3-methoxyphenyl)-2-methoxypropanoic acid
  • 1-(4-Chloro-3-methoxyphenyl)-2-fluoroethan-1-ol
  • 3-(4-Chloro-3-methoxyphenyl)propane-1-thiol
  • 3-Amino-3-(4-chloro-3-methoxyphenyl)cyclobutan-1-ol
  • 1-(2,6-Dichlorophenyl)-2-(methylamino)ethan-1-one
  • 3-(2-Chloro-6-fluorophenoxy)-3-methylazetidine
  • 3-(2-Chloro-6-fluorophenoxy)pyrrolidine
  • Methyl 3-amino-2-(2,6-dichlorophenyl)propanoate
  • 1-[2-(2,6-Dichlorophenyl)propan-2-yl]cyclopropan-1-amine
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